NCT03846713

Brief Summary

The purpose of this study is to investigate the effect of double-lumen tube thermal-softening before intubation on the success rate of tube exchange by airway exchange catheter.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
102

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Dec 2017

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 27, 2017

Completed
1 year until next milestone

First Submitted

Initial submission to the registry

January 9, 2019

Completed
1 month until next milestone

First Posted

Study publicly available on registry

February 20, 2019

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 31, 2019

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 31, 2019

Completed
Last Updated

June 25, 2025

Status Verified

June 1, 2025

Enrollment Period

1.3 years

First QC Date

January 9, 2019

Last Update Submit

June 19, 2025

Conditions

Keywords

double-lumen tubeintubationairway exchange catheterthermosoftening

Outcome Measures

Primary Outcomes (1)

  • Time to intubate

    Length of time to exchange endotracheal tube from single- to double-lumen tube using airway exchange catheter.

    Intraoperative (During exchanging single- to double-lumen tube)

Secondary Outcomes (3)

  • Postoperative hoarseness (4-points scoring)

    up to 48 hours after surgery

  • postoperative sore throat (4-points scoring)

    up to 48 hours after surgery

  • Vocal cord injuries assessed by videolaryngoscope

    up to 1 hour after double-lumen tube extubation

Study Arms (2)

non-thermosoftening

ACTIVE COMPARATOR

Double-lumen tube is put into a bottle of normal saline at room temperature (25°C) before intubation.

Procedure: non-thermosoftening

thermosoftening

EXPERIMENTAL

Double-lumen tube is put into a bottle of warm normal saline (40°C) before intubation.

Procedure: thermosoftening

Interventions

By using airway exchange catheter, tube exchange is performed from single to double lumen tube that was put into normal saline at room temperature.

non-thermosoftening

By using airway exchange catheter, tube exchange is performed from single to double lumen tube that was put into warm normal saline (40°C).

thermosoftening

Eligibility Criteria

Age20 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients undergoing thoracic surgery that requires bronchoscopy study before the placement of double-lumen tubes

You may not qualify if:

  • Preoperative hoarseness or a sore throat
  • History of upper airway diseases
  • Anticipated difficult airway

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Seoul National University Hospital

Seoul, Seoul, 110-744, South Korea

Location

MeSH Terms

Conditions

HoarsenessPharyngitis

Condition Hierarchy (Ancestors)

Voice DisordersLaryngeal DiseasesRespiratory Tract DiseasesRespiration DisordersOtorhinolaryngologic DiseasesNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and SymptomsSigns and Symptoms, RespiratoryRespiratory Tract InfectionsInfectionsPharyngeal DiseasesStomatognathic Diseases

Study Officials

  • Jae-Hyon Bahk, MD, PhD

    Seoul National University Hospital

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

January 9, 2019

First Posted

February 20, 2019

Study Start

December 27, 2017

Primary Completion

March 31, 2019

Study Completion

May 31, 2019

Last Updated

June 25, 2025

Record last verified: 2025-06

Locations