Sutures Versus Glue in Laparoscopic Port Site Closure.
STILS
The Use of Absorbable Suture Versus Tissue Glue in Laparoscopic Port Skin Closure. A Prospective, Randomised Control Trial. The STILS Trial.
1 other identifier
interventional
200
1 country
1
Brief Summary
Cosmesis postoperatively is an important consideration for both patients and surgeons and consequently surgeons have become increasingly interested in replacing conventional sutures by means of adhesive bonds for the closure of skin wounds. Therefore the investigators are using two different close techniques for laparoscopic wounds. These are; 1. sutures with steri-strips and 2. adhesive bond.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Feb 2019
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 11, 2019
CompletedFirst Submitted
Initial submission to the registry
February 12, 2019
CompletedFirst Posted
Study publicly available on registry
February 18, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 1, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
September 2, 2019
CompletedFebruary 20, 2019
February 1, 2019
5 months
February 12, 2019
February 18, 2019
Conditions
Outcome Measures
Primary Outcomes (1)
Cosmesis
Cosmetic outcome being graded by patient and clinician via questionnaire. Observer scar assessment form (1-10) 1 = worst result possible, 10 being the best result possible.
6 months
Secondary Outcomes (1)
Surgical site infection (SSI).
6 months
Study Arms (2)
Suture & steri-strips
ACTIVE COMPARATORAdhesive Glue
ACTIVE COMPARATORInterventions
sutures and steri-strips
Eligibility Criteria
You may qualify if:
- Elective Laparoscopic surgeries. Emergency Laparoscopic surgeries.
You may not qualify if:
- Contaminated wounds. immunocompromised patients. diabetic patients. history of Keloid scarring.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
St. James Hospital
Dublin, Ireland
Related Publications (1)
Ramjit SE, Davey MG, Keelan S, Herlihy E, Dromey M, Garvey C, Nugent TS, Fawaz A, O'Connell L, Cunningham M, Fahy M, Ryan EJ, Moran B, Aljohmani L, Narayanasamy J, Kelly ME, Healy C, Donohoe C, Ravi N, Neary P, Reynolds JV, Donlon NE. Evaluating the use of absorbable sutures versus sTaples versus tIssue glue in laparoscopic port skin closure (STILS) trial: A prospective, multi-centre randomised clinical trial (RCT). Surgeon. 2025 Oct;23(5):306-312. doi: 10.1016/j.surge.2025.02.015. Epub 2025 Mar 17.
PMID: 40102141DERIVED
MeSH Terms
Conditions
Interventions
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- General Surgery Specialist Registrar
Study Record Dates
First Submitted
February 12, 2019
First Posted
February 18, 2019
Study Start
February 11, 2019
Primary Completion
July 1, 2019
Study Completion
September 2, 2019
Last Updated
February 20, 2019
Record last verified: 2019-02
Data Sharing
- IPD Sharing
- Will not share