NCT03840876

Brief Summary

The key to a successful microlaryngoscopy is adequate operative field exposure and illumination. A variety of airway control procedures has been developed to improve operative exposure. A small size endotracheal tube is commonly used. However, some surgeon may suggest a 'no-tube' technique to optimize the surgical field. This study aims to investigate effectiveness and safety of a novel technique by supraglottic jet oxygenation and ventilation (SJOV) via nasal approach to facilitate optimal visualization in laser microlaryngeal surgery for small vocal polyps resection.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jan 2019

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2019

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

February 11, 2019

Completed
4 days until next milestone

First Posted

Study publicly available on registry

February 15, 2019

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2019

Completed
Last Updated

February 15, 2019

Status Verified

February 1, 2019

Enrollment Period

3 months

First QC Date

February 11, 2019

Last Update Submit

February 12, 2019

Conditions

Keywords

Jet VentilationSupraglotticIntranasalMicrolaryngeal Surgery

Outcome Measures

Primary Outcomes (1)

  • Numerical rating scale (NRS) rated by surgeon

    The surgeons rated surgical exposure and visualization on a numerical rating scale (NRS), ranging from 0 to 10, with 0 defined as the best condition and 10 as the worst.

    Immediately after surgery, the surgeons rated surgical exposure and visualization with NRS only once.

Secondary Outcomes (1)

  • Operation duration

    Immediately after surgery, the duration of the operation was recorded by the investigator.

Study Arms (2)

Group J

EXPERIMENTAL

Jet ventilation was achieved via supraglottic jet oxygenation and ventilation with WEI NASAL JET (WNJ).

Device: WEI NASAL JET (WNJ)

Group I

NO INTERVENTION

Patients were ventilated with a small size endotracheal tube.

Interventions

Jet ventilation was achieved with WEI NASAL JET (WNJ) connected to a manual jet ventilator (Driving pressure: 40 psi, fraction of inspired oxygen: 100% O2, Respiratory rate: 25/min, I/E ratio: 40%)

Group J

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Patients scheduled for laser laryngeal surgery under general anesthesia

You may not qualify if:

  • Patients with cardiac, pulmonary, hepatic, or renal dysfunction. Patients with nasal disease. Patients with anticipated difficult airway.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Eye, Ear, Nose and Throat Hospital

Shanghai, Shanghai Municipality, 200031, China

RECRUITING

Study Officials

  • Wenxian Li, M.D. Ph.D.

    Eye and ENT Hospital of Fudan University

    STUDY DIRECTOR

Central Study Contacts

Hui Qiao, M.D. Ph.D.

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Attending Anesthesiologist

Study Record Dates

First Submitted

February 11, 2019

First Posted

February 15, 2019

Study Start

January 1, 2019

Primary Completion

April 1, 2019

Study Completion

April 1, 2019

Last Updated

February 15, 2019

Record last verified: 2019-02

Locations