NCT03835143

Brief Summary

varicoclelectomy is done for subfertiltiy and varicocele induced orchialgia. The effect of varicocelectomy on semen analysis is controversial. Many articles report favorable outcomes and others do not. Most study don't focus on varicocelectomy done for varicocele induced orchialgia,and those studies dont report on postoperative semen. This study will focus on the effect of operation on the semen postoperatively .

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Mar 2019

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 4, 2019

Completed
4 days until next milestone

First Posted

Study publicly available on registry

February 8, 2019

Completed
1 month until next milestone

Study Start

First participant enrolled

March 12, 2019

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 12, 2019

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

January 12, 2020

Completed
Last Updated

April 27, 2020

Status Verified

April 1, 2020

Enrollment Period

6 months

First QC Date

February 4, 2019

Last Update Submit

April 23, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Grades of Motility of sperm in semen analysis

    semen analysis

    3 months after the operation

Secondary Outcomes (1)

  • Count of sperms in semen analysis

    3 months after the operation

Other Outcomes (2)

  • Pain improvement using Numeric Pain Rating Scale

    3 months after the operation

  • duppler

    3 months after the operation

Interventions

varicocele ligation done at the level of subinguinal region

Eligibility Criteria

Age20 Years - 60 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

there is no description

You may qualify if:

  • Primary varicocele.
  • Patient's age more than 20 years.
  • Normal semen analysis

You may not qualify if:

  • Secondary varicocele.
  • Recurrent varicocele.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Assuit Medical School

Asyut, Assuit, 71621, Egypt

Location

Related Publications (5)

  • Cayan S, Shavakhabov S, Kadioglu A. Treatment of palpable varicocele in infertile men: a meta-analysis to define the best technique. J Androl. 2009 Jan-Feb;30(1):33-40. doi: 10.2164/jandrol.108.005967. Epub 2008 Sep 4.

  • Kupis L, Dobronski PA, Radziszewski P. Varicocele as a source of male infertility - current treatment techniques. Cent European J Urol. 2015;68(3):365-70. doi: 10.5173/ceju.2015.642. Epub 2015 Oct 15.

  • Shabana W, Teleb M, Dawod T, Elsayed E, Desoky E, Shahin A, Eladl M, Sorour W. Predictors of improvement in semen parameters after varicocelectomy for male subfertility: A prospective study. Can Urol Assoc J. 2015 Sep-Oct;9(9-10):E579-82. doi: 10.5489/cuaj.2808. Epub 2015 Sep 9.

  • Paick S, Choi WS. Varicocele and Testicular Pain: A Review. World J Mens Health. 2019 Jan;37(1):4-11. doi: 10.5534/wjmh.170010. Epub 2018 May 16.

  • Cho CL, Esteves SC, Agarwal A. Novel insights into the pathophysiology of varicocele and its association with reactive oxygen species and sperm DNA fragmentation. Asian J Androl. 2016 Mar-Apr;18(2):186-93. doi: 10.4103/1008-682X.170441.

MeSH Terms

Conditions

Varicose VeinsCone-Rod Dystrophies

Condition Hierarchy (Ancestors)

Vascular DiseasesCardiovascular DiseasesEye Diseases, HereditaryEye DiseasesRetinal DystrophiesRetinal DegenerationRetinal DiseasesGenetic Diseases, InbornCongenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
resident of urology

Study Record Dates

First Submitted

February 4, 2019

First Posted

February 8, 2019

Study Start

March 12, 2019

Primary Completion

September 12, 2019

Study Completion

January 12, 2020

Last Updated

April 27, 2020

Record last verified: 2020-04

Locations