Brain Perfusion Assessment in the Acute Phase of Migraine Aura

NCT03821584 | Terminated

• 1 other identifier: RC18_0373
• Study Type: observational
• Target: 25
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of the study is to determine the proportion of patients with change in brain perfusion during the acute phase of migraine attack with aura.

Conditions

Emergencies

Keywords

migraine; perfusion arterial; aura brain

Outcome Measures

Primary Outcomes (1)

• Perfusion pattern of concerned brain areas

  Presence or absence of hypo-hyperperfusion using arterial spin labeling. Visual assessments and comparison between hemispheres

  1 hour

Secondary Outcomes (1)

• Pattern of perfusion and aura duration

  12 month

Interventions

the difference of care management and prognosis, an early distinction of migraine aura based on imaging techniques will have a particular interest OTHER

the difference of care management and prognosis, an early distinction of migraine aura based on imaging techniques will have a particular interest

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients admitted to the hospital with neurological deficit and final clinical diagnosis of migraine with aura (certain probable as defined by The International Classification of Headache Disorders)

You may qualify if:

• Age between greater than or equal to 18
• Able to undergo MRI during migraine aura

You may not qualify if:

• Pregnant females
• Contraindications towards MRI scanning
• History of epilepsy, psychiatric disease, or any other neurologic disease (brain tumors, stroke..).
• Presence of abnormalities on the MRI that could explain the neurological deficit.
• Adults under guardianship or trusteeship

Sponsors & Collaborators

• Nantes University Hospital: lead

Study Sites (1)

CHU Nantes

Nantes, 44000, France

Location

MeSH Terms

Conditions

Emergencies; Migraine Disorders

Condition Hierarchy (Ancestors)

Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Headache Disorders, Primary; Headache Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases

Study Officials

• Solene de Gaalon, Dr

  Nantes University Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 4, 2019
• First Posted: January 30, 2019
• Study Start: March 1, 2019
• Primary Completion: June 22, 2021
• Study Completion: July 22, 2021
• Last Updated: September 17, 2021

Record last verified: 2021-07

Locations

FR (1)