Whipple Procedure: A 5-year Clinical Experience in Tertiary Care Center

NCT03820583 | Completed

• 1 other identifier: s11
• Study Type: interventional
• Target: 57
• Locations: 1 country
• Sites: 1

Brief Summary

The study was conducted in tertiary care hospital of Lahore. Patient undergoing Whipple procedure were studied by compiling demographic details of the patients, common presenting symptoms, various indications for Whipple's procedure, the cofactors which affect the procedures outcome and morbidity and mortality of the patients.

Conditions

Whipple Procedure

Keywords

Whipple procedure, pancreatic carcinoma, biliary stenting,

Outcome Measures

Primary Outcomes (4)

• Percentage of patients developing pancreatic fistula

  Percentage of patients developing pancreatic fistula (pancreatic juice collected in drain rich in amylase) after Whipple procedure Enteric leak postoperative complications like pancreatic fistula, anastomotic leakage, hemorrhage, wound infection,mortality

  4 weeks

• Percentage of patients developing hemorrhage

  Percentage of patients developing hemorrhage after Whipple procedure

  2 weeks

• Percentage of patients developing wound infection

  Percentage of patients developing wound infection after Whipple procedure

  4 weeks

• Mortality rate

  Mortality of patients undergoing Whipple surgery

  6 weeks

Interventions

Whipple Procedure PROCEDURE

Patients underwent Whipple procedure for pancreatic tumors. The procedure commenced with rooftop incision. then layers of abdomen dissected to reach the peritoneum. Then Duodenum dissected out along with pancreas and common bile duct. After rescetion of these structures the anatomy of the tract restored with three anastomosis namely pancreaticojejunostomy, gastrojejunostomy and choledochojejunostomy/hepaticojejunostomy.

Eligibility Criteria

• Age: 20 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• patients of both sexes with age ranging from 20 years to 70 years
• patients with pancreatic tumors
• patients with adequate cardiorespiratory reserves to be fit for prolong general anesthesia

You may not qualify if:

• unresectable tumors
• unfit for surgery

Sponsors & Collaborators

• Services Hospital, Lahore: lead

Study Sites (1)

Services hospital

Lahore, Punjab Province, 54000, Pakistan

Location

MeSH Terms

Conditions

Pancreatic Neoplasms

Interventions

Pancreaticoduodenectomy

Condition Hierarchy (Ancestors)

Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Endocrine Gland Neoplasms; Digestive System Diseases; Pancreatic Diseases; Endocrine System Diseases

Intervention Hierarchy (Ancestors)

Digestive System Surgical Procedures; Surgical Procedures, Operative

Study Officials

• Mahmmood Ayyaz, mbbs, fcps

  Services Hospital, Lahore

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principle investigator

Model Details: Patients undergoing Whipple procedure due to pancreatic tumor were included in the study

Study Record Dates

• First Submitted: January 25, 2019
• First Posted: January 29, 2019
• Study Start: January 1, 2014
• Primary Completion: December 31, 2018
• Study Completion: December 31, 2018
• Last Updated: January 31, 2019

Record last verified: 2019-01

Locations

PA (1)