Application of High Flow Nasal Cannula for Prevention of Post-extubation Atelectasis in Children Undergoing Surgery
Seoul National University Hospital Department of Anesthesiology and Pain Medicine
1 other identifier
interventional
80
1 country
1
Brief Summary
postoperative atelectasis observation by ultrasound after application of high flow nasal cannula oxygenation
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Mar 2019
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
January 23, 2019
CompletedFirst Posted
Study publicly available on registry
January 25, 2019
CompletedStudy Start
First participant enrolled
March 2, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 30, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
June 30, 2021
CompletedMarch 7, 2019
March 1, 2019
1.9 years
January 23, 2019
March 5, 2019
Conditions
Outcome Measures
Primary Outcomes (1)
lung sound score
0: Normal aeration (N): presence of lung sliding with A lines or fewer than two isolated B lines 1. Moderate loss of lung aeration: multiple well-defined B lines (B1 lines) 2. Severe loss of lung aeration: multiple coalescent B lines (B2 lines) 3. Lung consolidation (C): the presence of a tissue pattern characterized by dynamic air
30 minutes after arrival of postanesthetic care unit
Study Arms (2)
nasal prong
PLACEBO COMPARATORconventional nasal prong application after the surgery in postanesthetic care unit (PACU)
high flow nasal cannula oxygenation
EXPERIMENTALhigh flow nasal cannula application after the surgery in postanesthetic care unit (PACU)
Interventions
high flow nasal cannula application in PACU
Eligibility Criteria
You may qualify if:
- general anesthesia
You may not qualify if:
- preterm
- bronchopulmonary dysplasia
- upper respiratory infection history
- respiratory disease
- cardiac surgery
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Seoul National University Hospital
Seoul, South Korea
Related Publications (1)
Lee JH, Ji SH, Jang YE, Kim EH, Kim JT, Kim HS. Application of a High-Flow Nasal Cannula for Prevention of Postextubation Atelectasis in Children Undergoing Surgery: A Randomized Controlled Trial. Anesth Analg. 2021 Aug 1;133(2):474-482. doi: 10.1213/ANE.0000000000005285.
PMID: 33181560DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Hee-Soo Kim
Seoul National University Children's Hospital
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- TRIPLE
- Who Masked
- PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- principle investigator
Study Record Dates
First Submitted
January 23, 2019
First Posted
January 25, 2019
Study Start
March 2, 2019
Primary Completion
January 30, 2021
Study Completion
June 30, 2021
Last Updated
March 7, 2019
Record last verified: 2019-03