NCT03816566

Brief Summary

BresoTEC has designed and developed a standalone wearable device (the patch), that can record tracheal sounds with a microphone attached just above the suprasternal notch of the subject.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Dec 2018

Shorter than P25 for not_applicable

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 23, 2018

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

January 23, 2019

Completed
2 days until next milestone

First Posted

Study publicly available on registry

January 25, 2019

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 23, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 23, 2019

Completed
Last Updated

January 25, 2019

Status Verified

January 1, 2019

Enrollment Period

8 months

First QC Date

January 23, 2019

Last Update Submit

January 23, 2019

Conditions

Outcome Measures

Primary Outcomes (1)

  • Estimation of AHI

    Validate the performance of the patch in estimating the AHI compared to an in-laboratory PSG.

    8 months

Secondary Outcomes (1)

  • Estimation of body position

    8 months

Study Arms (1)

Wearable Device and PSG

EXPERIMENTAL

The device under investigation (the patch) will be used in patients undergoing overnight polysomnography simultaneously, to compare the accuracy of the investigational device against the gold standard for the diagnosis of sleep apnea.

Device: patch

Interventions

patchDEVICE

A standalone wearable device (the patch), that can record tracheal sounds with a microphone attached just above the suprasternal notch of the subject. The patch also has a 3-dimensional accelerometer to record body position. Furthermore, the patch records oxygen saturation using an FDA cleared pulse oximeter, Nonin 3150 WristOx2® with Bluetooth Low Energy.

Wearable Device and PSG

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Toronto Rehabilitation Institute

Toronto, Ontario, M5G 2A2, Canada

RECRUITING

Toronto General Hospital

Toronto, Ontario, M5G 2C4, Canada

NOT YET RECRUITING

MeSH Terms

Conditions

Sleep Apnea Syndromes

Interventions

Transdermal Patch

Condition Hierarchy (Ancestors)

ApneaRespiration DisordersRespiratory Tract DiseasesSleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System Diseases

Intervention Hierarchy (Ancestors)

Equipment and Supplies

Study Officials

  • Clodagh Ryan, MD

    Toronto General Hospital & Toronto Rehabilitation Institute

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Hisham Alshaer, MD, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Masking
NONE
Masking Details
The outcome assessor performing the automatic analysis of the patch data will be blinded to the PSG scores performed by the Sleep Lab Technicians. The principal investigator responsible for the completion and closing of the study according to the protocol will be blinded to the patch AHI automatic analysis. Similarly, the Sleep Lab Technicians scoring the PSG will be blinded to the patch automatic analysis. By the end of recruiting the target sample size, the data will be un-blinded and statistical analysis will be performed.
Purpose
DIAGNOSTIC
Intervention Model
SEQUENTIAL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 23, 2019

First Posted

January 25, 2019

Study Start

December 23, 2018

Primary Completion

August 23, 2019

Study Completion

August 23, 2019

Last Updated

January 25, 2019

Record last verified: 2019-01

Locations