NCT03807375

Brief Summary

The aim of the study was to evaluate the preoxygenation time by observing patients undergoing preoxygenation with CPAP (Continuous Positive Airway Pressure) and Mask Ventilation in the clinic.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Mar 2018

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2018

Completed
11 months until next milestone

First Submitted

Initial submission to the registry

January 10, 2019

Completed
6 days until next milestone

First Posted

Study publicly available on registry

January 16, 2019

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2019

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2019

Completed
Last Updated

July 5, 2019

Status Verified

January 1, 2019

Enrollment Period

1.2 years

First QC Date

January 10, 2019

Last Update Submit

July 2, 2019

Conditions

Keywords

CPAP(Continuous Positive Airway Pressure)Standard preoxygenation

Outcome Measures

Primary Outcomes (2)

  • Prevention of desaturation during intubation

    Prevent desaturation of the apnea period during endotracheal intubation in bariatric surgery

    5 minutes

  • prevention of side effects of hypoxia

    hypoxia-induced arrhythmia hypotension tachycardia

    10 minutes

Study Arms (2)

CPAP

OTHER

During preoxygenation, the ventilator device will be placed in spontaneous mode and set as CPAP: 5 cmH2O. The process will continue until the end-tidal O2 concentration ≥ 90% is removed.

Other: CPAP preoxygenation

standard preoxygenation

NO INTERVENTION

During the preoxygenation, the ventilator device will be put in spontaneous mode and the procedure will continue until the End-tidal O2 concentration ≥90% is removed without additional pressure.

Interventions

During preoxygenation, the ventilator device will be placed in spontaneous mode and set as CPAP: 5 cmH2O.

CPAP

Eligibility Criteria

Age20 Years - 50 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Patients between the ages of 20 and 50 years
  • American Society of Anesthesiologists I, II or III
  • Patients with body mass index of 40 and over

You may not qualify if:

  • cardiopulmonary disease
  • patients with previous abdominal or thoracic surgery or cerebrovascular disease
  • story of intracranial hypertension or epilepsy
  • patients with a story of difficult tracheal intubation

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Diskapi Yildirim Beyazit Training Research Hospital

Ankara, Turkey (Türkiye)

Location

Related Publications (2)

  • Bouroche G, Bourgain JL. Preoxygenation and general anesthesia: a review. Minerva Anestesiol. 2015 Aug;81(8):910-20. Epub 2015 Jun 5.

    PMID: 26044934BACKGROUND
  • Nimmagadda U, Salem MR, Crystal GJ. Preoxygenation: Physiologic Basis, Benefits, and Potential Risks. Anesth Analg. 2017 Feb;124(2):507-517. doi: 10.1213/ANE.0000000000001589.

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
principle investigator

Study Record Dates

First Submitted

January 10, 2019

First Posted

January 16, 2019

Study Start

March 1, 2018

Primary Completion

May 1, 2019

Study Completion

June 1, 2019

Last Updated

July 5, 2019

Record last verified: 2019-01

Data Sharing

IPD Sharing
Will not share

Locations