NCT03804632

Brief Summary

A prospective observational multi center study to assess the level of asthma control at Primary Care Setting; government health clinics (Klinik Kesihatan) in Malaysia. The specific objective of the study is to assess, in real-life clinical practice in Malaysia, the level of asthma control and the potential risk factors for uncontrolled disease in asthma patients treated at government health clinics.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,011

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Oct 2017

Shorter than P25 for all trials

Geographic Reach
1 country

10 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 23, 2017

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 6, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 6, 2018

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

January 14, 2019

Completed
1 day until next milestone

First Posted

Study publicly available on registry

January 15, 2019

Completed
Last Updated

May 31, 2019

Status Verified

May 1, 2019

Enrollment Period

8 months

First QC Date

January 14, 2019

Last Update Submit

May 30, 2019

Conditions

Outcome Measures

Primary Outcomes (1)

  • Level of GINA-defined asthma control

    GINA-defined asthma control: According to clinical characteristics that include daytime symptoms, limitations of activity, nocturnal symptoms/awakening, need for reliever/rescue treatment. Patient's are classified as controlled, partially controlled or uncontrolled.

    up to 8 months

Secondary Outcomes (3)

  • Types of medication prescribed for asthma control

    up to 8 months

  • Asthma control level

    up to 8 months

  • Adherence level in patients with inhalers

    up to 8 months

Study Arms (1)

GINA-defined clinical diagnosis of Asthma

All patients with GINA-defined clinical diagnosis of Asthma seen at respiratory clinic from October to December 2017 with age 18 and above

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Outpatients seen and treated by health care providers at government health clinics.

You may qualify if:

  • Malaysians who have been diagnosed with Asthma by a physician verified by an investigator and seen at government health clinic (Klinik Kesihatan) from October - December 2017
  • Be at least 18 years of age

You may not qualify if:

  • Clinical features suggesting emphysema or chronic bronchitis and other chronic lung diagnosis
  • Pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (10)

Research Site

Port Dickson, Negeri Sembilan, Malaysia

Location

Research Site

Seremban, Negeri Sembilan, Malaysia

Location

Research Site

Pantai Remis, Perak, Malaysia

Location

Research Site

George Town, Pulau Pinang, Malaysia

Location

Research Site

Kota Kinabalu, Sabah, Malaysia

Location

Research Site

Asajaya, Sarawak, Malaysia

Location

Research Site

Banting, Selangor, Malaysia

Location

Research Site

Rawang, Selangor, Malaysia

Location

Research Site

Bandar Permaisuri, Terengganu, Malaysia

Location

Research Site

Kuala Terengganu, Terengganu, Malaysia

Location

Related Publications (1)

  • Mohd Isa NA, Cheng CL, Nasir NH, Naidu V, Gopal VR, Alexander AK. Asthma control and asthma treatment adherence in primary care: results from the prospective, multicentre, non-interventional, observational cohort ASCOPE study in Malaysia. Med J Malaysia. 2020 Jul;75(4):331-337.

Related Links

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 14, 2019

First Posted

January 15, 2019

Study Start

October 23, 2017

Primary Completion

June 6, 2018

Study Completion

June 6, 2018

Last Updated

May 31, 2019

Record last verified: 2019-05

Locations