NCT03793894

Brief Summary

Lung cancer suffers from large racial and socioeconomic disparities. Yet those at the highest risk of lung cancer death - current smokers, blacks, and individuals with low socioeconomic status (SES) and negative social determinants of health (SDH) - are less likely to receive preventive health services, including the two most effective interventions to reduce lung cancer mortality: tobacco dependence treatment and lung cancer screening (LCS) with low-dose computed tomography (LDCT). At Boston Medical Center (BMC) these preventive services are grossly underutilized, in part due to barriers our patients face in accessing these outpatient programs. Innovative approaches are needed to guide high-risk smokers to post-discharge early lung cancer detection services. The overarching goal of this study is to reduce disparities in lung cancer morbidity and mortality by using hospitalization at an urban safety net hospital as an opportunity to connect high-risk smokers to both LDCT lung cancer screening and tobacco dependence treatment. In addition to inpatient shared decision making \[SDM\] by an NP using a decision aid, screen-eligible smokers will also be connected with a community health worker (CHW) to facilitate access to outpatient smoking cessation counseling and LCS (CHW navigation).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
21

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Feb 2019

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 3, 2019

Completed
1 day until next milestone

First Posted

Study publicly available on registry

January 4, 2019

Completed
1 month until next milestone

Study Start

First participant enrolled

February 12, 2019

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 28, 2020

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 4, 2020

Completed
Last Updated

July 7, 2020

Status Verified

July 1, 2020

Enrollment Period

12 months

First QC Date

January 3, 2019

Last Update Submit

July 6, 2020

Conditions

Keywords

Community health worker (CHW)Shared decision making (SDM)Low-dose computed tomography (LDCT)

Outcome Measures

Primary Outcomes (1)

  • LDCT screening within 3 months post randomization

    Data will be collected from the electronic health record (EHR) and the BMC lung cancer screening (LDCT) database.

    3 months

Secondary Outcomes (3)

  • Knowledge of LDCT screening

    baseline, 24 hours post enrollment

  • Self-report smoking cessation

    6 months

  • Biochemical validated smoking cessation

    6 months

Study Arms (2)

Enhanced usual care

ACTIVE COMPARATOR

All trial participants will receive smoking cessation counseling (standard of care) and will be given the AHRQ "Is Lung Cancer Screening Right for me?" patient decision aid to review independently while in the hospital.

Behavioral: Smoking Cessation CounselingBehavioral: Decision Aid

Inpatient SDM + CHW Navigation

EXPERIMENTAL

In addition to the smoking cessation counseling and decision aid received by all subjects, intervention subjects will receive shared decision making (SDM) + CHW navigation.

Behavioral: Smoking Cessation CounselingBehavioral: Decision AidBehavioral: Shared decision making (SDM)Behavioral: CHW Navigation

Interventions

All participants will receive inpatient smoking cessation counseling by the tobacco-trained NP. Inpatient smoking cessation counseling is the standard of care at BMC.

Enhanced usual careInpatient SDM + CHW Navigation
Decision AidBEHAVIORAL

The AHRQ "Is Lung Cancer Screening Right for me?" patient decision aid is a 4-page paper format with the following features: 1) LDCT screening harms and benefits information, written in plain language and using pictographs, easily understood by those with low health literacy; 2) prompts to clarify patient values and preferences and to stimulate discussion about tradeoffs; 3) clear quit smoking messaging and resources (1-800-QUIT-NOW)

Enhanced usual careInpatient SDM + CHW Navigation

During the smoking cessation consultation, the nurse practitioner (NP) will conduct SDM, using the 4-page AHRQ "Is Lung Cancer Screening Right for me?" decision aid as a guide. The purpose of SDM is three-fold: 1) conduct a tailored discussion on tradeoffs of LDCT screening, consistent with Centers for Medicare \& Medicaid Services (CMS) requirements for SDM using a decision aid; 2) directly connect interested patients to LDCT screening; 3) to empower and motivate patients to quit smoking within the LDCT screening context.

Inpatient SDM + CHW Navigation
CHW NavigationBEHAVIORAL

The CHW will meet with the participant after the SDM to initiate the coordination of outpatient tobacco treatment, referral to LCS, and resources to address the barriers to preventive services. The CHW will follow patients subjects in the intervention arm for 3 months to help navigate and address negative social determinants of health that are barriers to LCS and tobacco treatment. For patients who agree to screening, the CHW will schedule the appointment, arrange the transportation to appointment, and meet participant at the appointment to facilitate the screening.

Inpatient SDM + CHW Navigation

Eligibility Criteria

Age55 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Hospitalized smoker at BMC
  • Meeting LDCT screening eligibility criteria: (age 55-80 years; ≥30-pack years smoking)
  • Current smoker (\> 1 cigarette per day)
  • Able to speak, read, and understand English
  • Able and willing to comply with all study protocols and procedures
  • Having a PCP in the BMC network or one of the affiliated health centers

You may not qualify if:

  • Inability to tolerate surgical resection of a lung cancer, as defined by home oxygen therapy (an indicator of severe lung cancer or heart disease)
  • Active cancer (receiving treatment/new diagnosis) in prior 3 months or advanced stage cancer
  • Signs and symptoms of lung cancer or prior diagnosis of lung cancer
  • Already had chest CT (LDCT screening or other chest CT) in the past year
  • Pregnant

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Boston Medical Center

Boston, Massachusetts, 02118, United States

Location

Related Publications (1)

  • Kathuria H, Gunawan A, Spring M, Aijaz S, Cobb V, Fitzgerald C, Wakeman C, Howard J, Clancy M, Foreman AG, Truong V, Wong C, Steiling K, Lasser KE, Bulekova K, Wiener RS. Hospitalization as an opportunity to engage underserved individuals in shared decision-making for lung cancer screening: results from two randomized pilot trials. Cancer Causes Control. 2022 Nov;33(11):1373-1380. doi: 10.1007/s10552-022-01620-8. Epub 2022 Aug 23.

MeSH Terms

Conditions

Smoking Cessation

Interventions

Decision Support Techniques

Condition Hierarchy (Ancestors)

Health BehaviorBehavior

Intervention Hierarchy (Ancestors)

Investigative Techniques

Study Officials

  • Hasmeena Kathuria, MD

    Boston Medical Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 3, 2019

First Posted

January 4, 2019

Study Start

February 12, 2019

Primary Completion

January 28, 2020

Study Completion

June 4, 2020

Last Updated

July 7, 2020

Record last verified: 2020-07

Data Sharing

IPD Sharing
Will not share

Locations