Evaluation of the Links Between Sleep Disorders and the Risk of Suicide Attempt

NCT03793699 | Unknown

• 2 other identifiers: 2017_552017-A03649-44
• Study Type: observational
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

Several studies have demonstrated an association between sleep disorders such as insomnia and nightmares to suicidal ideations and behaviors. Nevertheless, some of these studies are methodologically questionable especially in the exploration of sleep disorders. Furthermore, confounding factors such as depressive symptomatology are not controlled and the measurement of suicidal behavior has often been taken into account as a historical measure, not as a current event, which introduces uncertainties and a lack of precision regarding the temporality of the phenomena. Today, while the links between sleep disorders and suicidal risk are well known, we have a lack of information on the importance and the role of sleep disorders as a precipitating factor. Indeed, few studies have evaluated the temporal link between sleep disorders and suicidal acts. The objective of this study is to evaluate the links between acute and chronic sleep disorders and the risk of suicide attempt

Conditions

Attempted Suicide

Keywords

Suicide; Suicidal ideation; Sleep disorder

Outcome Measures

Primary Outcomes (1)

• Sleep disorders intensity by the Insomnia Severity Index (ISI)

  ISI score in the last 2 weeks between a group of suicide attempts and a group with suicidal thoughts suicidal The Insomnia Severity Index has seven questions. The seven answers are added up to get a total score.

  at the 48 hours after the hospitalization; at the maximum within 72 hours.

Secondary Outcomes (6)

• Correlation between Beck Suicide Intent Scale (BSIS) score and ISI score

  Baseline (visit inclusion) and at one month ago

• Evolution of ISI score

  At one month +/- 15 days ant at 3 months +/-3 weeks

• Chronotype classification by MCTQ

  at the 48 hours after the hospitalization; at the maximum within 72 hours;at 3 months +/-3 weeks

• Pittsburg Sleep Quality Index (PSQI) score

  at the 48 hours after the hospitalization; at the maximum within 72 hours,at 3 months +/-3 weeks

• Childhood Trauma Questionnaire (CTQ) score

  at the 48 hours after the hospitalization; at the maximum within 72 hours.

Study Arms (2)

case group : realized a suicide attempt

adults having realized a suicide attempt and without histories of suicide attempt.

control group : only suicidal ideas

adults having suicidal ideas without suicidal acting out and without histories of suicide attempt.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The population in the study is a population of adults having realized a suicide attempt and without histories of suicide attempt. She(it) will be compared with a population of adults having suicidal ideas without suicidal acting out and without histories of suicide attempt.

You may qualify if:

• Criterion specific to the studying group :
• \- Subjects hospitalized and whose indication of hospitalization is a suicide attempt by voluntary drug intoxication or phlebotomy during the last 72 hours, without any history of attempted suicide
• Criterion specific to the control group:
• \- Subjects hospitalized since less than 72 hours, and whose indication of hospitalization is the presence of suicidal ideas, without any history of attempted suicide

You may not qualify if:

• Pregnant of lactating women
• Diagnosed dementia pathology
• Proven intellectual disability
• Patient whose physical or mental state does not allow the passing of the tests of the study
• Under protective measures (guardianship/supervision)
• Refusal to participate in the study
• Diagnosed with chronic or severe psychiatric illness (psychotic disorder, bipolarity)

Sponsors & Collaborators

• University Hospital, Lille: lead

Study Sites (1)

Hôpital Fontan, CHU

Lille, France

RECRUITING

MeSH Terms

Conditions

Suicide, Attempted; Suicide; Suicidal Ideation; Sleep Wake Disorders

Condition Hierarchy (Ancestors)

Self-Injurious Behavior; Behavioral Symptoms; Behavior; Nervous System Diseases; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Mental Disorders

Study Officials

• Vincent JARDON, MD

  University Hospital, Lille

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Vincent JARDON, MD

CONTACT

320 44 45 84; vincent.jardon@chru-lille.fr

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 16, 2018
• First Posted: January 4, 2019
• Study Start: February 4, 2019
• Primary Completion: December 1, 2022
• Study Completion: December 1, 2022
• Last Updated: September 11, 2020

Record last verified: 2020-09

Locations

FR (1)