D Mannose for Prevention and Treatment of RUTIs

NCT03790254 | Completed

• 1 other identifier: ReviewUTIs
• Study Type: observational
• Target: 500
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this review is to address clinical reliability, efficacy and safety of long-term treatment with oral D Mannose for the prevention of recurrent urinary tract infections (RUTIs) in females.

Conditions

Recurrent Urinary Tract Infections; Antibiotic Prophylaxis; Antibiotic Resistance

Keywords

recurrent urinary tract infections; d mannose prophylaxis; antibiotic prophylaxis

Outcome Measures

Primary Outcomes (1)

• research literature data on d mannose for prevention and treatment of recurrent urinary tract infections.

  literature search of the Medline, Embase, and Cochrane Library databases

  January 2010-December 2018

Interventions

systematic review OTHER

Eligibility Criteria

• Age: 18 Years - 90 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Search strategy and selection criteria Only publications with the text and/or the abstract written in the English language were considered. Additional papers cited in the references of the search manuscripts were further examined. Articles not addressing topics of interest were excluded, and the full text of the remaining articles was examined. Our literature search identified 15 articles pertaining to the search terms (Word variations have been searched). Further analysis of these articles resulted in 11 clinical trials which were deemed relevant to our review. The retrieved studies were assessed for their relevance based on the title and abstracts. Finally, studies references were screened in order to identify eventually unknown studies.

You may qualify if:

• recurrent urinary tract infections (RUTIs)

You may not qualify if:

• Upper urinary tract infections, severe clinical symptoms, fever \> 37,5 with lumbar pain

Sponsors & Collaborators

• Fondazione IRCCS Policlinico San Matteo di Pavia: lead

Study Sites (1)

Urology Department Fondazione IRCCS Policlinico San Matteo

Pavia, 27100, Italy

Location

MeSH Terms

Conditions

Urinary Tract Infections

Condition Hierarchy (Ancestors)

Infections; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases

Study Officials

• Daniele Porru, MD

  Fondazione IRCCS Policlinico San Matteo

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: MD

Study Record Dates

• First Submitted: December 26, 2018
• First Posted: December 31, 2018
• Study Start: January 1, 2010
• Primary Completion: December 20, 2018
• Study Completion: December 25, 2018
• Last Updated: December 31, 2018

Record last verified: 2018-12

Data Sharing

• IPD Sharing: Will not share

Locations

IT (1)