Coexistence of Cerebral and Coronary Atherosclerosis in Acute Ischemic Cerebrovascular Disease Patients Registry
CoCCA
1 other identifier
observational
500
1 country
1
Brief Summary
Coexistence of Cerebral and Coronary Atherosclerosis in Acute Ischemic Cerebrovascular Disease Patients Registry (CoCCA) is a single-center observational registry of patients hospitalized for acute ischemic cerebrovascular disease (AICVD) with atherosclerotic changes in both cerebral and coronary arteries. This registry aims to establish quantified risk stratification and prognostic models, as well as suggest effective diagnostic and therapeutic strategies.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2019
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
December 25, 2018
CompletedFirst Posted
Study publicly available on registry
December 27, 2018
CompletedStudy Start
First participant enrolled
January 12, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2027
ExpectedJanuary 11, 2022
January 1, 2022
4.9 years
December 25, 2018
January 7, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Rate of Major Adverse Cardiovascular Events
cardiovascular mortality (any mortality due to ischemic stroke, myocardial infarction, other cardiac diseases, or unobserved sudden death), ischemic stroke, myocardial infarction and unstable angina
1 year
Secondary Outcomes (11)
Rate of Major Adverse Cardiovascular Events
90 days
Functional Outcome
90 days
Rate of Ischemic Stroke
1 year
Rate of Acute Coronary Syndrome
1 year
Rate of Cardiovascular Mortality
1 year
- +6 more secondary outcomes
Study Arms (1)
AICVD patients with CoCCA
acute ischemic cerebrovascular disease patients with coexistence of cerebral and coronary atherosclerosis.
Interventions
observational only- no intervention
Eligibility Criteria
acute ischemic cerebrovascular disease patients with coexistence of cerebral and coronary atherosclerosis
You may qualify if:
- Diagnosed as ischemic stroke or transient ischemic attack (TIA).
- Less than 30 days after onset of ischemic stroke or TIA symptoms.
- Extracranial or intracranial cerebral atherosclerosis confirmed by vascular ultrasound or CT angiograpgy or MR angiograpgy or digital substraction angiography.
- Coronary atherosclerosis confirmed by CT angiograpgy or MR angiograpgy or digital substraction angiography; or with myocardial ischemia symptoms confirmed using electrocardiogram or echocardiography or cardiac MR; or with a history of percutaneous coronary intervention or coronary artery bypass graft.
You may not qualify if:
- With malignant tumors or poor organ functions or hematologic diseases, whose estimated life expectancy is less than 5 years.
- Patients refuse to participate in the research.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Xuanwu Hospital, Capital Medical University
Beijing, BJ, 100053, China
Biospecimen
anticoagulant peripheral blood, serum
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 5 Years
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal investigator
Study Record Dates
First Submitted
December 25, 2018
First Posted
December 27, 2018
Study Start
January 12, 2019
Primary Completion
December 1, 2023
Study Completion (Estimated)
December 1, 2027
Last Updated
January 11, 2022
Record last verified: 2022-01