Estimation of Economic Consequences Linked With Different Care Management Pathways of Differentiated Thyroid Cancers

NCT03787121 | Completed

• 1 other identifier: RC31/17/0378
• Study Type: observational
• Target: 361
• Locations: 1 country
• Sites: 1

Brief Summary

The incidence of Thyroid Cancer (TC) has increased over the last thirty years, in France and worldwide. This increase is mainly due to good prognosis microPapillary TC (mPTC). Sixty percent of diagnosed cancers are considered as over-diagnosed, leading to an over-treatment of these cases. The increase of diagnosis of mPTC and its treatment inevitably leads to an increase of medical resources consumption and corresponding costs. The primary aim of this study is to estimate the cost related to different care management pathway of TC patient during a lifetime period using a multi-state Markov model. This is a retrospective, observational population based cohort study, using data from a cohort study of TC patients implemented by the ONCOMIP network which initially aimed to perform an audit of clinical practices for the management of TC, and from database of the French social health insurance of Midi-Pyrenees region to calculate observed costs of TC management during 24 months.

Conditions

Thyroid Cancer

Keywords

health economics; care management pathways; overtreatment

Outcome Measures

Primary Outcomes (1)

• cost related to the different management pathways of TC patient

  estimate the cost related to the different management pathways of TC patient during a lifetime period using a multi-state Markov model

  24 months

Interventions

care management pathways PROCEDURE

different care management pathways, including thyroidectomy, iode 131, hormonal treatment and type of follow up

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The Evathyr database collected by the Oncomip network: Cohort describing the initial management of 423 patients with TC diagnosed in 2014 and passed in the process of Multidisciplinary Team Meeting (MTM).

You may qualify if:

• all patients with a good prognosis of the TC
• diagnosed in 2014
• whose medical file discussed in MultiDisciplinary Team Meeting (MDTM) in Midi-Pyrenees

You may not qualify if:

• patients whose surgical management was carried out outside Midi Pyrenees are excluded and other morphological types are excluded (medullar, anaplastic, lymphomas, sarcomas)

Sponsors & Collaborators

• University Hospital, Toulouse: lead

Study Sites (1)

University HospitalToulouse

Toulouse, France

Location

MeSH Terms

Conditions

Thyroid Neoplasms

Condition Hierarchy (Ancestors)

Endocrine Gland Neoplasms; Neoplasms by Site; Neoplasms; Head and Neck Neoplasms; Endocrine System Diseases; Thyroid Diseases

Study Officials

• Nadège Costa, PhD

  University Hospital, Toulouse

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 24, 2018
• First Posted: December 26, 2018
• Study Start: April 1, 2019
• Primary Completion: December 31, 2020
• Study Completion: December 31, 2020
• Last Updated: August 27, 2021

Record last verified: 2021-08

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)