NCT03768076

Brief Summary

single institution cases series review of histological and clinical data

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
220

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Nov 2018

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 22, 2018

Completed
8 days until next milestone

Study Start

First participant enrolled

November 30, 2018

Completed
7 days until next milestone

First Posted

Study publicly available on registry

December 7, 2018

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 28, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 28, 2019

Completed
Last Updated

August 5, 2021

Status Verified

July 1, 2021

Enrollment Period

3 months

First QC Date

November 22, 2018

Last Update Submit

July 30, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • retrospective analysis of cases of Parosteal osteosarcoma

    Investigators will exam the presence of progression (dedifferentiation) areas and the relationship of these factors to individual outcome.

    at baseline (Day0)

Eligibility Criteria

Sexall
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

male and female with diagnosis of parosteal osteosarcoma treated at Rizzoli institute from 01 Jan 1900 to 31 Jul 2018

You may qualify if:

  • Male and female patients treated at Rizzoli Institute from 01 Jan 1900 to 31 Jul 2018
  • Diagnosis of parosteal osteosarcoma
  • Written informed consent prior to any study-specific analysis and/or data collection

You may not qualify if:

  • Patients with histological diagnosis different from parosteal osteosarcoma

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Istituto ortopedico Rizzoli

Bologna, 40136, Italy

Location

Related Publications (4)

  • Han I, Oh JH, Na YG, Moon KC, Kim HS. Clinical outcome of parosteal osteosarcoma. J Surg Oncol. 2008 Feb 1;97(2):146-9. doi: 10.1002/jso.20902.

  • Bertoni F, Bacchini P, Staals EL, Davidovitz P. Dedifferentiated parosteal osteosarcoma: the experience of the Rizzoli Institute. Cancer. 2005 Jun 1;103(11):2373-82. doi: 10.1002/cncr.21039.

  • Okada K, Frassica FJ, Sim FH, Beabout JW, Bond JR, Unni KK. Parosteal osteosarcoma. A clinicopathological study. J Bone Joint Surg Am. 1994 Mar;76(3):366-78. doi: 10.2106/00004623-199403000-00007.

  • Laitinen M, Parry M, Albergo JI, Jeys L, Abudu A, Carter S, Sumathi V, Grimer R. The prognostic and therapeutic factors which influence the oncological outcome of parosteal osteosarcoma. Bone Joint J. 2015 Dec;97-B(12):1698-703. doi: 10.1302/0301-620X.97B12.35749.

MeSH Terms

Conditions

Osteosarcoma, Juxtacortical

Condition Hierarchy (Ancestors)

OsteosarcomaNeoplasms, Bone TissueNeoplasms, Connective TissueNeoplasms, Connective and Soft TissueNeoplasms by Histologic TypeNeoplasmsSarcoma

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 22, 2018

First Posted

December 7, 2018

Study Start

November 30, 2018

Primary Completion

February 28, 2019

Study Completion

February 28, 2019

Last Updated

August 5, 2021

Record last verified: 2021-07

Data Sharing

IPD Sharing
Will not share

No Individual Patient Data sharing plan has been implemented

Locations