Noninvasive Assessment of Intravascular Volume Status for Postoperative Patients

NCT03766451 | Unknown

• 1 other identifier: Hebatullah Negm Eldeen
• Study Type: observational
• Target: 35
• Locations: 1 country
• Sites: 1

Brief Summary

Ultrasound measurements of the inferior vena cava (IVC) have been proposed as a noninvasive tool to help guide fluid management. Well-established correlations exist between respiratory cycle-induced changes in IVC diameter and C entral Venous Pressure (CVP) . Beyond providing an estimate of CVP, the caval index, or percentage collapsibility of the IVC , has been proposed as a predictor of preload reserve. This noninvasive rapid measurement of CVP is especially important in critical care settings. It can help in differentiating hypovolemic, septic and cardiogenic shock. Changes in volume status will be depicted by change in the diameter of the IVC . However, the validity and reliability of sonographic assessment of the inferior vena cava have been matters of controversy, and its applicability has been shown to be limited by technical difficulties. Recent study has shown a significant relationship between the internal jugular vein/common carotid artery (IJV/CCA) cross-sectional area ratio and CVP in pediatric burn patients .

Conditions

Intravascular Volume

Outcome Measures

Primary Outcomes (1)

• The correlation between (Internal Jugular Vein/Common Carotid Artery Cross-Sectional Area Ratio),and Inferior Vena Cava Diameter by using ultrasound

  The correlation between (Internal Jugular Vein/Common Carotid Artery Cross-Sectional Area Ratio),and Inferior Vena Cava Diameter by using ultrasound

  immediately upon admission to surgical intensive care unit and after acchieving cvp above 8 cmh2o by saline infusion (10 ml/kg) average 3 hours after admission

Eligibility Criteria

• Age: 20 Years - 60 Years
• Sex: all
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

Patients scheduled for elective or emergency major surgeries (e.g., abdominal exploration, cancer bladder, cancer rectum, cancer stomach and aorto-femoral bypass grafting) who require post-operative SICU admission for close monitoring and assessment of volume status will be considered for enrollment.

You may qualify if:

• ASA physical status I and II
• Patients who are able to breathe spontaneously and lay supine post-operative.
• Patients who had CVP catheter (subclavian or internal jugular vein)

You may not qualify if:

• Chronic obstructive or restrictive pulmonary disease. 2-Significant cardiac disease 3-Significant hepatic disease 4-Renal impairment ( creatinine \>2 mg/dl). 5- BMI ˃ 30 kg/m2 6- Pneumothorax or mediastinal masses. 7- mechanical ventilation or coming with tracheostomy. 8- defect at the site of sonography. 9- Pregnancy. 10- Instability of vital signs 11- Unwillingness to participate 12- sepsis or septic shock. 13- neurosurgical interventions

Sponsors & Collaborators

• Beni-Suef University: lead

Study Sites (1)

Hebatullah Negm Eldeen

Banī Suwayf, 11311, Egypt

RECRUITING

Study Officials

• Hebatullah Negm eldeen, A.L.

  Beni-Suef University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant lecturer

Study Record Dates

• First Submitted: November 28, 2018
• First Posted: December 6, 2018
• Study Start: November 10, 2018
• Primary Completion: November 1, 2019
• Study Completion: November 1, 2019
• Last Updated: December 6, 2018

Record last verified: 2018-12

Locations

EG (1)