The Incidence of Difficult Intubation in Obese Versus Non-obese Patients

NCT03752593 | Completed DMC

• 1 other identifier: KHUH/Anesthesia
• Study Type: observational
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of our study is to identify the incidence of difficult endotracheal intubation in patients with normal BMI undergoing surgery under general anaesthesia in our hospital and compare it to that of obese patients.

Conditions

Airway Obstruction

Outcome Measures

Primary Outcomes (1)

• Assessment of difficulty in airway management

  Assessment of Cormack Lehanne grading (intubation difficulty scale) IDS.

  two years

Study Arms (2)

Obese

Patients with a BMI of greater than 30 who are presenting to the hospital for any surgical procedure requiring general anesthesia

Other: ET Tube

Non-Obese

Patients with a BMI of less than 30 who are presenting to the hospital for any surgical procedure requiring general anesthesia

Other: ET Tube

Interventions

ET Tube OTHER

Patients with a BMI of greater than 30 or less than who are presenting to the hospital for any surgical procedure requiring general anesthesia

Non-Obese; Obese

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Heterogeneous group representing the general population of Muharraq

You may qualify if:

• Elective surgery
• BMI\< 30 for Normal BMI group
• BMI \> 30 for Obese group

You may not qualify if:

• Known previous difficult airway
• Pediatric patients.
• Emergency patients

Sponsors & Collaborators

• King Hamad University Hospital, Bahrain: lead

Study Sites (1)

King Hamad University Hospital

Al Muharraq, 24343, Bahrain

Location

Related Publications (13)

• Murphy C, Wong DT. Airway management and oxygenation in obese patients. Can J Anaesth. 2013 Sep;60(9):929-45. doi: 10.1007/s12630-013-9991-x. Epub 2013 Jul 9.

  PMID: 23836064 BACKGROUND

• Lundstrom LH. Detection of risk factors for difficult tracheal intubation. Dan Med J. 2012 Apr;59(4):B4431.

  PMID: 22459727 BACKGROUND

• Shiga T, Wajima Z, Inoue T, Sakamoto A. Predicting difficult intubation in apparently normal patients: a meta-analysis of bedside screening test performance. Anesthesiology. 2005 Aug;103(2):429-37. doi: 10.1097/00000542-200508000-00027.

  PMID: 16052126 BACKGROUND

• Lavi R, Segal D, Ziser A. Predicting difficult airways using the intubation difficulty scale: a study comparing obese and non-obese patients. J Clin Anesth. 2009 Jun;21(4):264-7. doi: 10.1016/j.jclinane.2008.08.021. Epub 2009 Jun 6.

  PMID: 19502026 BACKGROUND

• Kim WH, Ahn HJ, Lee CJ, Shin BS, Ko JS, Choi SJ, Ryu SA. Neck circumference to thyromental distance ratio: a new predictor of difficult intubation in obese patients. Br J Anaesth. 2011 May;106(5):743-8. doi: 10.1093/bja/aer024. Epub 2011 Feb 24.

  PMID: 21354999 BACKGROUND

• De Jong A, Molinari N, Pouzeratte Y, Verzilli D, Chanques G, Jung B, Futier E, Perrigault PF, Colson P, Capdevila X, Jaber S. Difficult intubation in obese patients: incidence, risk factors, and complications in the operating theatre and in intensive care units. Br J Anaesth. 2015 Feb;114(2):297-306. doi: 10.1093/bja/aeu373. Epub 2014 Nov 27.

  PMID: 25431308 BACKGROUND

• Juvin P, Lavaut E, Dupont H, Lefevre P, Demetriou M, Dumoulin JL, Desmonts JM. Difficult tracheal intubation is more common in obese than in lean patients. Anesth Analg. 2003 Aug;97(2):595-600. doi: 10.1213/01.ANE.0000072547.75928.B0.

  PMID: 12873960 BACKGROUND

• Hashim MM, Ismail MA, Esmat AM, Adeel S. Difficult tracheal intubation in bariatric surgery patients, a myth or reality? Br J Anaesth. 2016 Apr;116(4):557-8. doi: 10.1093/bja/aew039. No abstract available.

  PMID: 26994235 BACKGROUND

• Karkouti K, Rose DK, Wigglesworth D, Cohen MM. Predicting difficult intubation: a multivariable analysis. Can J Anaesth. 2000 Aug;47(8):730-9. doi: 10.1007/BF03019474.

  PMID: 10958088 BACKGROUND

• Brodsky JB, Lemmens HJ, Brock-Utne JG, Vierra M, Saidman LJ. Morbid obesity and tracheal intubation. Anesth Analg. 2002 Mar;94(3):732-6; table of contents. doi: 10.1097/00000539-200203000-00047.

  PMID: 11867407 BACKGROUND

• Bond A. Obesity and difficult intubation. Anaesth Intensive Care. 1993 Dec;21(6):828-30. doi: 10.1177/0310057X9302100614. No abstract available.

  PMID: 8122742 BACKGROUND

• Benumof JL. Management of the difficult adult airway. With special emphasis on awake tracheal intubation. Anesthesiology. 1991 Dec;75(6):1087-110. doi: 10.1097/00000542-199112000-00021.

  PMID: 1824555 BACKGROUND

• Cormack RS, Lehane J. Difficult tracheal intubation in obstetrics. Anaesthesia. 1984 Nov;39(11):1105-11.

  PMID: 6507827 BACKGROUND

MeSH Terms

Conditions

Airway Obstruction

Condition Hierarchy (Ancestors)

Respiratory Insufficiency; Respiration Disorders; Respiratory Tract Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Director of Research

Study Record Dates

• First Submitted: November 21, 2018
• First Posted: November 26, 2018
• Study Start: November 8, 2016
• Primary Completion: October 8, 2018
• Study Completion: November 8, 2018
• Last Updated: October 22, 2019

Record last verified: 2019-10

Locations

BA (1)