NCT03751085

Brief Summary

This study is to establish a new, alternative stereotactic biopsy frame (AW frame) in the field of stereotactic neurosurgery.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
15

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jul 2018

Typical duration for not_applicable

Geographic Reach
1 country

3 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 18, 2018

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

November 16, 2018

Completed
7 days until next milestone

First Posted

Study publicly available on registry

November 23, 2018

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 17, 2020

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2020

Completed
Last Updated

November 23, 2018

Status Verified

November 1, 2018

Enrollment Period

2 years

First QC Date

November 16, 2018

Last Update Submit

November 20, 2018

Conditions

Keywords

AW framebiopsystereotacticaccuracysafety

Outcome Measures

Primary Outcomes (2)

  • Diagnostic yield

    The diagnostic yield is defined as the number of patients in whom the histopathological diagnosis was made based of the biological material obtained during the biopsy.

    For each patient 2 week after the biopsy

  • Number of participants presenting with post-biopsy complications

    The presence of acute postoperative complication is noted if any of following findings is present: wound site infection up to two weeks after the biopsy, a new neurological deficit developed up to 24 hours following the operation and present in a follow up clinical examination 2 weeks postoperatively, intraparenchymal hematoma with radiological evidence.

    an average of 2 week

Secondary Outcomes (2)

  • Time

    From the time of the participant is transferred to the OR until the time of the participant transfer out of it, assessed on the day of operation.

  • Length of hospital stay

    an average of 1 week

Study Arms (1)

AW frame

EXPERIMENTAL

AW frame biopsy

Device: AW frame

Interventions

AW frameDEVICE

AW stereotactic frame for intracranial lesion biopsy

AW frame

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age \>17 years old
  • Radiological diagnosis of intracranial space occupying lesion of any etiology

You may not qualify if:

  • Patient involved in other study trial
  • Any serious medical condition that according to the investigator could interfere with the conduct of the study
  • Unwillingness or inability to comply with study requirements

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Department of Neurosurgery, Sarawak General Hospital

Kuching, Sarawak, 93586, Malaysia

RECRUITING

Hospital Miri

Miri, Sarawak, 98000, Malaysia

NOT YET RECRUITING

Department of Neurosurgery, Hospital Sibu

Sibu, Sarawak, 96000, Malaysia

NOT YET RECRUITING

MeSH Terms

Conditions

Brain Diseases

Condition Hierarchy (Ancestors)

Central Nervous System DiseasesNervous System Diseases

Central Study Contacts

Bik Liang Lau, MD

CONTACT

Albert Sii Hieng Wong, FRACS

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr.

Study Record Dates

First Submitted

November 16, 2018

First Posted

November 23, 2018

Study Start

July 18, 2018

Primary Completion

July 17, 2020

Study Completion

December 31, 2020

Last Updated

November 23, 2018

Record last verified: 2018-11

Data Sharing

IPD Sharing
Will not share

Locations