NCT03746951

Brief Summary

The investigators aim to compare the use of a suprainguinal fascia iliaca compartment block vs lumbar plexus block as an adjunct to general anesthesia in pediatric patients undergoing orthopedic procedures involving the hip or upper femur. This study will help determine the efficacy of the two techniques and their advantages when compared to each other including time to perform the block, opioid consumption reduction, effects on postoperative pain, and the length of stay.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
15

participants targeted

Target at below P25 for phase_2

Timeline
Completed

Started Apr 2019

Shorter than P25 for phase_2

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 16, 2018

Completed
4 days until next milestone

First Posted

Study publicly available on registry

November 20, 2018

Completed
5 months until next milestone

Study Start

First participant enrolled

April 24, 2019

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 31, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 31, 2020

Completed
2.1 years until next milestone

Results Posted

Study results publicly available

March 3, 2022

Completed
Last Updated

March 3, 2022

Status Verified

February 1, 2022

Enrollment Period

9 months

First QC Date

November 16, 2018

Results QC Date

February 9, 2022

Last Update Submit

February 9, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Total Time to Perform the Regional Anesthesia Technique

    The amount of time if takes to perform either the FICB or LPB.

    Baseline

Secondary Outcomes (2)

  • Opioid Consumption in the PACU

    Immediately to 1 hour post-op

  • Post-op Pain Scores

    48 hours post-op

Study Arms (2)

Fascia iliaca compartment block (FICB)

ACTIVE COMPARATOR

FICB is a local anesthetic nerve block, a type of local anesthesia, used for the hip, thigh, and knee. It is performed by inserting the needle into the groin.

Drug: Ropivacaine Hcl 0.5% Inj Vil 20Ml

Lumbar plexus block (LPB)

ACTIVE COMPARATOR

LPB is a local anesthetic nerve block, a type of local anesthesia, used for the hip, thigh, and knee. It is performed by inserting the needle into the back.

Drug: Ropivacaine Hcl 0.5% Inj Vil 20Ml

Interventions

Anesthetic agent used in peripheral nerve block

Also known as: Naropin
Fascia iliaca compartment block (FICB)Lumbar plexus block (LPB)

Eligibility Criteria

Age2 Years - 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • ASA grade I-III
  • Undergoing elective orthopedic surgical procedures involving the hip and upper thigh

You may not qualify if:

  • Local anesthetic allergy
  • Skin or localized infection at the site of catheter insertion
  • Patient or parent refusal

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Nationwide Children's Hospital

Columbus, Ohio, 43205, United States

Location

MeSH Terms

Conditions

Musculoskeletal Diseases

Interventions

Ropivacaine

Intervention Hierarchy (Ancestors)

AnilidesAmidesOrganic ChemicalsAniline CompoundsAmines

Results Point of Contact

Title
Dr. Senthil Krishna
Organization
Nationwide Children's Hospital

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, CARE PROVIDER, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Attending Anesthesiologist

Study Record Dates

First Submitted

November 16, 2018

First Posted

November 20, 2018

Study Start

April 24, 2019

Primary Completion

January 31, 2020

Study Completion

January 31, 2020

Last Updated

March 3, 2022

Results First Posted

March 3, 2022

Record last verified: 2022-02

Data Sharing

IPD Sharing
Will not share

Locations