COMPARATIVE STUDY OF THE EFFICACY OF HYALURONIC ACID, DRY NEEDLING AND COMBINED TREATMENT IN PATELLAR OSTEOARTHRITIS

NCT03743818 | Completed DMC

• 1 other identifier: UCAvila
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

Randomized clinical trial in patients with knee osteoarthritis. Sixty patients will be evaluated, divided in three groups (20 in each). One group A will be treated by dry needling in the vast internal, other group B will be treated with a standardized treatment protocol (electrotherapy and manual therapy), and group C will be treated with hialuronic acid. The investigators want to observe which technique is the most effective in osteoarthritis.

Conditions

Osteoarthritis

Outcome Measures

Primary Outcomes (1)

• Visual Analog Scale

  Pain 0 maximum pain score---------10 minimum pain score

  1 month

Secondary Outcomes (2)

• Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC scale)

  1 month

• International Physical Activity Questionnaire scale

  1 month

Study Arms (3)

dry needling

EXPERIMENTAL

dry needling in trigger point in vastus medialis of quadriceps

Device: dry needling

standardized treatment protocol

ACTIVE COMPARATOR

in the standardized treatment protocol the investigators including ultrasound, tens, and isometric quadriceps contractions

Other: ultrasound

hialuronic acid

ACTIVE COMPARATOR

infiltration of hyaluronic acid in the affected knee

Device: hyauluronic acid

Interventions

dry needling DEVICE

dry needling on the trigger point of the vastus medialis of the quadriceps

dry needling

ultrasound OTHER

aply ultrasound on the knee

standardized treatment protocol

hyauluronic acid DEVICE

aply hyaluronic acid on the knee

hialuronic acid

Eligibility Criteria

• Age: 18 Years - 55 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Patients with knee pain and diagnosed of osteoarthritis knee and confirm RNM
• More 18 years.
• Less 55 years

You may not qualify if:

• More 55 years.
• Less 18 years.
• mental dysfunction
• those who have any type of complication that can cause myofascial or neuropathic pain in the lower limb, such as lumbo-sacral radiculopathy, neuropraxia, neurothymesis, axonotmesis, or meralgia paraesthetica; who have any condition generally considered to be a factor in perpetuating TrPs, such as fibromyalgia, hypothyroidism, or iron deficiency; and patients who may have a fear of needles (belonephobia) will be excluded.
• Patients with lower limb dysmetries of 0.50 cm or more were also excluded from this study.

Sponsors & Collaborators

• Universidad Católica de Ávila: lead
• Verónica Prieto Domínguez: collaborator
• Raúl Vittori: collaborator
• Ignacio Normand Farias: collaborator

Study Sites (1)

Fisiosalud Avila

Ávila, 05003, Spain

Location

Related Publications (4)

• Velazquez-Saornil J, Ruiz-Ruiz B, Rodriguez-Sanz D, Romero-Morales C, Lopez-Lopez D, Calvo-Lobo C. Efficacy of quadriceps vastus medialis dry needling in a rehabilitation protocol after surgical reconstruction of complete anterior cruciate ligament rupture. Medicine (Baltimore). 2017 Apr;96(17):e6726. doi: 10.1097/MD.0000000000006726.

  PMID: 28445290 RESULT

• Sanchez-Romero EA, Pecos-Martin D, Calvo-Lobo C, Ochoa-Saez V, Burgos-Caballero V, Fernandez-Carnero J. Effects of dry needling in an exercise program for older adults with knee osteoarthritis: A pilot clinical trial. Medicine (Baltimore). 2018 Jun;97(26):e11255. doi: 10.1097/MD.0000000000011255.

  PMID: 29952993 RESULT

• Espi-Lopez GV, Serra-Ano P, Vicent-Ferrando J, Sanchez-Moreno-Giner M, Arias-Buria JL, Cleland J, Fernandez-de-Las-Penas C. Effectiveness of Inclusion of Dry Needling in a Multimodal Therapy Program for Patellofemoral Pain: A Randomized Parallel-Group Trial. J Orthop Sports Phys Ther. 2017 Jun;47(6):392-401. doi: 10.2519/jospt.2017.7389. Epub 2017 May 13.

  PMID: 28504067 RESULT

• Mayoral O, Salvat I, Martin MT, Martin S, Santiago J, Cotarelo J, Rodriguez C. Efficacy of myofascial trigger point dry needling in the prevention of pain after total knee arthroplasty: a randomized, double-blinded, placebo-controlled trial. Evid Based Complement Alternat Med. 2013;2013:694941. doi: 10.1155/2013/694941. Epub 2013 Mar 27.

  PMID: 23606888 RESULT

MeSH Terms

Conditions

Osteoarthritis

Interventions

Dry Needling; High-Energy Shock Waves

Condition Hierarchy (Ancestors)

Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases

Intervention Hierarchy (Ancestors)

Complementary Therapies; Therapeutics; Physical Therapy Modalities; Ultrasonic Waves; Sound; Radiation, Nonionizing; Radiation; Physical Phenomena

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: principal investigator

Study Record Dates

• First Submitted: November 11, 2018
• First Posted: November 16, 2018
• Study Start: July 8, 2020
• Primary Completion: December 15, 2020
• Study Completion: April 20, 2021
• Last Updated: April 28, 2021

Record last verified: 2021-04

Data Sharing

• IPD Sharing: Will not share

Locations

ES (1)