Impact of Clinical Pharmacy Services Provided for Patients With Active Rheumatoid Arthritis

NCT03743181 | Completed DMC

• 1 other identifier: 156
• Study Type: observational
• Target: 54
• Locations: 1 country
• Sites: 1

Brief Summary

Enrolment of clinical pharmacy services in RA patients as a part of health care system has been investigated at many studies but not investigated in active RA patients before. This study aimed to detect drug therapy-related problems (DTRPs) in active rheumatoid arthritis (RA) patients and Investigate the impact of clinical pharmacist interventions on the patient clinical outcome and quality of life (QoL). Methods:Prospective, randomized controlled study to be carried out at rheumatology outpatient clinic, Ain Shams University Hospitals on 50 patients with active RA for 6 months.determine if any drug therapy problems are present.Develop a plan of care that includes interventions to resolve drug therapy problems, achieve goals of therapy, and prevent drug therapy problems. questionnaires was used to measure functional status in RA patients using health assessment questionnaire (HAQ) and assess self-reported quality of life in patients with (RA) using rheumatoid arthritis quality of life questionnaire (RAQOL) and measure adherence using the 4-item Morisky Green Levine Medication Adherence Scale and Disease Activity Score-28 was used as an objective method to assess RA disease activity.

Conditions

Rheumatoid Arthritis

Outcome Measures

Primary Outcomes (3)

• disease activity score

  disease activity score-28 (DAS-28) for measuring disease activity in rheumatoid arthritis patients

  6 months

• Quality of life questionnaire

  Rheumatoid arthritis quality of life questionnaire (RAQOL) for measuring quality of life

  6 months

• Health assessment questionnaire

  Health assessment questionnaire (HAQ) for measuring functional status in rheumatoid arthritis patients

  6 months

Study Arms (2)

intervention

will be supplied by pharmaceutical care services provided by the clinical pharmacist plus standard care by physician in attendance.

Other: pharmaceutical care services

control

will received standard care by physician in attendance

Interventions

pharmaceutical care services OTHER

detection of drug therapy problems and investigation of the impact of clinical pharmacist interventions on the patient clinical outcome and quality of life

intervention

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

rheumatoid arthritis patients from outpatient clinics - Ain shams university hospitals

You may qualify if:

• Patients aged 18-60 years old
• fulfillment of the American College of Rheumatology /European league against rheumatism (2010 ACR/EULAR ) diagnostic criteria for RA.
• patients with active RA(defined by DAS28 score \< 5.1)

You may not qualify if:

• Patients with cognitive impairment.
• The presence of hepatic or renal disease.
• The presence of other rheumatic and connective tissue disorders.

Sponsors & Collaborators

• hager omar mohammed siddik: lead

Study Sites (1)

Facuty of Pharmacu Ain Shams University

Cairo, Abasiya, 11566, Egypt

Location

MeSH Terms

Conditions

Arthritis, Rheumatoid

Interventions

Pharmaceutical Services

Condition Hierarchy (Ancestors)

Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases; Connective Tissue Diseases; Skin and Connective Tissue Diseases; Autoimmune Diseases; Immune System Diseases

Intervention Hierarchy (Ancestors)

Health Services; Health Care Facilities Workforce and Services

Study Officials

• hager omar m siddik

  teaching assistant at faculty of pharmacy ain shams university

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Teaching assistant at clinical pharmacy department at faculty of pharmacy ain shams university

Study Record Dates

• First Submitted: November 4, 2018
• First Posted: November 16, 2018
• Study Start: January 14, 2018
• Primary Completion: October 10, 2019
• Study Completion: December 18, 2019
• Last Updated: January 13, 2020

Record last verified: 2020-01

Locations

EG (1)