NCT03742934

Brief Summary

Video capsule endoscopy (VCE) is a noninvasive diagnostic tool used to assess the small bowel pathology. The diagnostic value of VCE is mostly dependent on the cleanliness of the colon. Investigators are aimed to prospectively assess the quality of bowel preparation in pediatric patients receiving short peptide diet versus those receiving liquid diet.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
210

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jan 2019

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 13, 2018

Completed
2 days until next milestone

First Posted

Study publicly available on registry

November 15, 2018

Completed
2 months until next milestone

Study Start

First participant enrolled

January 1, 2019

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2019

Completed
Last Updated

February 17, 2020

Status Verified

February 1, 2020

Enrollment Period

12 months

First QC Date

November 13, 2018

Last Update Submit

February 13, 2020

Conditions

Keywords

Bowel preparation

Outcome Measures

Primary Outcomes (1)

  • Cleansing score

    Cleansing scores were recorded according to a predetermined criterion

    assessed through study completion, an average of 1 year

Secondary Outcomes (2)

  • Diagnostic yield

    assessed through study completion, an average of 1 year

  • Completion rate

    assessed through study completion, an average of 1 year

Other Outcomes (2)

  • Adverse events

    assessed through study completion, an average of 1 year

  • Bristol scores

    assessed through study completion, an average of 1 year

Study Arms (2)

Formula group

EXPERIMENTAL

short peptide formula prior to capsule endoscopy

Other: Short peptide

Control group

OTHER

regular liquid diet

Other: Liquid diet

Interventions

Short peptide formula during bowel preparation

Formula group

Liquid diet during bowel preparation

Control group

Eligibility Criteria

Age3 Years - 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Indications of capsule endoscopy;
  • Informed consent form obtained.

You may not qualify if:

  • Contraindication of capsule endoscopy;
  • Unwilling to participate;
  • Formula allergy;
  • Unable to swallow the capsule.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Children's hospital of Fudan university

Shanghai, Shanghai Municipality, 201102, China

Location

Related Publications (2)

  • Goyal J, Goel A, McGwin G, Weber F. Analysis of a grading system to assess the quality of small-bowel preparation for capsule endoscopy: in search of the Holy Grail. Endosc Int Open. 2014 Sep;2(3):E183-6. doi: 10.1055/s-0034-1377521. Epub 2014 Jul 16.

    PMID: 26134966BACKGROUND
  • van Tuyl SA, den Ouden H, Stolk MF, Kuipers EJ. Optimal preparation for video capsule endoscopy: a prospective, randomized, single-blind study. Endoscopy. 2007 Dec;39(12):1037-40. doi: 10.1055/s-2007-966988.

    PMID: 18072052BACKGROUND

Study Officials

  • Ying Huang, PhD

    Children's Hospital of Fudan University

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
The director of gastroenterology of Children's Hospital of Fudan University

Study Record Dates

First Submitted

November 13, 2018

First Posted

November 15, 2018

Study Start

January 1, 2019

Primary Completion

December 31, 2019

Study Completion

December 31, 2019

Last Updated

February 17, 2020

Record last verified: 2020-02

Data Sharing

IPD Sharing
Will not share

Locations