Energy Intake, Exercise and Energy Replacement

NCT03742622 | Completed

• 1 other identifier: CHU-415
• Study Type: interventional
• Target: 14
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of the present study is to compare the effect of an exercise alone versus. An exercise followed by the ingestion of an energy replacement snack on the following energy intake, food reward and appetite feelings in adolescents with obesity.

Conditions

Pediatric Obesity

Keywords

appetite control; obesity; Adolescents; exercise; Energy replacement

Outcome Measures

Primary Outcomes (1)

• Energy intake measured during an ad libitum buffet meal (in kcal).

  food intake will be measured ad libitum during a lunch buffet. The adolescents will be offered an ad libitum buffet-type meal composed based on their food intake preferences. Their intake will be weighted using an electronic food scale by a member of the investigation team and then analysed using Bilnuts software

  at lunch (at day 1)

Secondary Outcomes (2)

• Measurement of hunger feelings

  at day 1

• Food reward

  at day 1

Study Arms (1)

Obese adolescents

EXPERIMENTAL

18 adolescents with obesity are involved and will perform the three conditions

Behavioral: CON . control condition without exercise / rest condition; Behavioral: EX. Condition with an acute exercise set in the middle of the morning; Behavioral: EX+R. condition with an acute exercise set in the morning and followed by a energy replacement snack

Interventions

CON . control condition without exercise / rest condition BEHAVIORAL

CON . Control condition without exercise / rest condition. The adolescents will be asked to remain quiet and at rest during the morning and will receive an ad libitum meal at lunch and dinner times. Their food reward will be assessed before and after lunch. Their appetite feelings will be assessed at regular intervals.

Obese adolescents

EX. Condition with an acute exercise set in the middle of the morning BEHAVIORAL

EX. Condition with an acute exercise set in the middle of the morning The adolescents will be asked to complete a 30 minutes exercise set at 65% of their capacities (cycling) in the morning and will receive an ad libitum meal at lunch and dinner times. Their food reward will be assessed before and after lunch. Their appetite feelings will be assessed at regular intervals

Obese adolescents

EX+R. condition with an acute exercise set in the morning and followed by a energy replacement snack BEHAVIORAL

EX+R. condition with an acute exercise set in the morning and followed by a energy replacement snack The adolescents will be asked to complete a 30 minutes exercise set at 65% of their capacities (cycling) in the morning followed by a snack that will cover the whole exercise-induced energy expenditure. They will then receive an ad libitum meal at lunch and dinner times. Their food reward will be assessed before and after lunch. Their appetite feelings will be assessed at regular intervals.

Obese adolescents

Eligibility Criteria

• Age: 12 Years - 16 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• BMI percentile \> 97th percentile according to the french curves.
• ages 12-16 years old
• Signed consent form
• being registered in the national social security system
• no contraindication to physical activity

You may not qualify if:

• Previous surgical interventions that is considered as non-compatible with the study.
• Diabetes
• weight loss during the last 6 months
• cardiovascular disease or risks

Sponsors & Collaborators

• University Hospital, Clermont-Ferrand: lead
• Tza Nou - Maison médicale pour enfants et adolescentes - 230, rue Vercingétorix - B.P. 77 - 63150 La Bourboule: collaborator
• SSR Nutrition-Obésité - 33-35 rue Maréchal Leclerc - 63000 Clermont-Ferrand: collaborator
• Université d'Auvergne: collaborator

Study Sites (1)

Chu Clermont-Ferrand

Clermont-Ferrand, 63003, France

Location

Related Publications (1)

• Moore H, Pereira B, Fillon A, Miguet M, Masurier J, Beaulieu K, Finlayson G, Thivel D. The association between obesity severity and food reward in adolescents with obesity: a one-stage individual participant data meta-analysis. Eur J Nutr. 2024 Jun;63(4):1241-1255. doi: 10.1007/s00394-024-03348-4. Epub 2024 Feb 20.

  PMID: 38376518 DERIVED

MeSH Terms

Conditions

Pediatric Obesity; Obesity; Motor Activity

Interventions

Exercise

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Behavior

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Yves BOIRIE

  University Hospital, Clermont-Ferrand

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Masking Details: no masking
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 6, 2018
• First Posted: November 15, 2018
• Study Start: November 17, 2018
• Primary Completion: March 3, 2019
• Study Completion: March 3, 2019
• Last Updated: September 12, 2019

Record last verified: 2019-09

Locations

FR (1)