NCT03741413

Brief Summary

Rh negative blood group is a rare blood group in China, as it only accounts for 0.3-0.4 percent of the Han population. Therefore, low inventory is often found in blood collection and supply agencies in many regions in China. On July 18, 2018 blood stockpile of O-negative and B-negative in Guangzhou Blood Center reached the warning line, and we took measures for emergency recruitment. O-negative and B-negative blood donors whose last donation dates were between January 1, 2015 and December 31, 2017 were identified and randomly assigned to three groups. Three different recruitment text messages were send to these groups respectively. At the same time, A-negative and AB-negative blood donors were marked as control group. We observed the re-donation rates among four groups within three months.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
2,074

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jul 2018

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 18, 2018

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 18, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 18, 2018

Completed
24 days until next milestone

First Submitted

Initial submission to the registry

November 11, 2018

Completed
3 days until next milestone

First Posted

Study publicly available on registry

November 14, 2018

Completed
Last Updated

May 5, 2020

Status Verified

May 1, 2020

Enrollment Period

3 months

First QC Date

November 11, 2018

Last Update Submit

May 2, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Re-donation rate

    Intention-to-treat were applied. Re-donation rate was defined as the number of donors in each group devided by donors who re-donated within 3 months.

    3 months

Study Arms (4)

Gain-frame SMS

EXPERIMENTAL

SMS messages "Dear Rh negative blood donors: Hello! As the Rh negative O/B blood stockpile is low now, but patients who are this blood type are in urgent need. If you are available, we hope that you can offer a helping hand to save their lives. Thank you for your support." were send to donors in this group.

Other: Gain-frame SMS

Loss-frame SMS

EXPERIMENTAL

SMS messages "Dear Rh negative blood donors: Hello! As the Rh negative O/B blood stockpile is low now, but patients who are this blood type are in urgent need. If you are available, we hope that you can offer a helping hand to prevent them from death. Thank you for your support." were send to donors in this group.

Other: Loss-frame SMS

Control SMS

EXPERIMENTAL

SMS messages "Dear Rh negative blood donors: Hello! As the Rh negative O/B blood stockpile is low now, but patients who are this blood type are in urgent need. If you are available, we hope that you can donate blood again. Thank you for your support." were send to donors in this group.

Other: Control SMS

Control group

NO INTERVENTION

Donors in this group were not received SMS reminders.

Interventions

Emergency recruitment cell phone short messages that emphasizing donating blood can save patients' lives were sent to donors in this group.

Gain-frame SMS

Emergency recruitment cell phone short messages emphasizing that donating blood can prevent patients from death were sent to donors in this group.

Loss-frame SMS

Emergency recruitment cell phone short messages that only mentioning the low Rh-negative blood stockpile were sent to donors in this group.

Control SMS

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Rh- negative blood donors whose last donations were between January 1, 2015 and December 31, 2017.

You may not qualify if:

  • Donors with an obviously invalid phone number. Donors whose serological results of the last donation were positive.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Guangzhou Blood Center

Guangzhou, Guangdong, 510095, China

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MS

Study Record Dates

First Submitted

November 11, 2018

First Posted

November 14, 2018

Study Start

July 18, 2018

Primary Completion

October 18, 2018

Study Completion

October 18, 2018

Last Updated

May 5, 2020

Record last verified: 2020-05

Data Sharing

IPD Sharing
Will not share

Locations