NCT03740776

Brief Summary

Eosinophils (EOS) in peripheral blood are significantly decreased in ST-segment elevation myocardial infarction (STEMI) and the reduced EOS indicates severe myocardial damage. Whether EOS is a good predictor for in-hospital major adverse cardiac events (MACEs) of patients with ST-segment elevation myocardial infarction remains unknown. The aims of this study was to evaluate prognostic role of EOS for in-hospital MACEs in STEMI patients who have undergone primary percutaneous coronary intervention (PCI)

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
2

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Oct 2015

Typical duration for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2015

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2017

Completed
1.3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2018

Completed
6 days until next milestone

First Submitted

Initial submission to the registry

November 7, 2018

Completed
7 days until next milestone

First Posted

Study publicly available on registry

November 14, 2018

Completed
Last Updated

November 14, 2018

Status Verified

November 1, 2018

Enrollment Period

1.8 years

First QC Date

November 7, 2018

Last Update Submit

November 13, 2018

Conditions

Outcome Measures

Primary Outcomes (1)

  • major adverse cardiac events

    the relationship between reduced eosinophils percentage and in-hospital MACE

    The median time of 7 days

Eligibility Criteria

Age20 Years - 85 Years
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

STEMI Patients

You may qualify if:

  • Patients with STEMI who underwent PCI within 12 hours from symptom onset
  • Patients from whom informed consent has been properly obtained in writing prior to start of the trial.

You may not qualify if:

  • Patients with previous myocardial infarction, congenital heart disease
  • Patients with liver disease, and renal failure
  • Patients with immunologic disease, malignant tumors, pregnancy, infection caused by various pathogens, chronic inflammatory disease, trauma.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

ST Elevation Myocardial Infarction

Condition Hierarchy (Ancestors)

Myocardial InfarctionMyocardial IschemiaHeart DiseasesCardiovascular DiseasesVascular DiseasesInfarctionIschemiaPathologic ProcessesPathological Conditions, Signs and SymptomsNecrosis

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

November 7, 2018

First Posted

November 14, 2018

Study Start

October 1, 2015

Primary Completion

August 1, 2017

Study Completion

November 1, 2018

Last Updated

November 14, 2018

Record last verified: 2018-11