NCT03738631

Brief Summary

This study evaluates cardiac biomarkers and their association to coronary artery disease in marathon runners.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
43

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Aug 2018

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 17, 2018

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

September 21, 2018

Completed
2 months until next milestone

First Posted

Study publicly available on registry

November 13, 2018

Completed
4.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2022

Completed
Last Updated

May 8, 2024

Status Verified

May 1, 2024

Enrollment Period

4.3 years

First QC Date

September 21, 2018

Last Update Submit

May 7, 2024

Conditions

Coronary Artery Disease

Outcome Measures

Primary Outcomes (2)

  • Cardiac Troponin-T level after marathon

    Cardiac troponin-T levels (ng/L), \[electrochemiluminescence (ECLIA) method\]

    0-30minutes after finishing the Paavo Nurmi Marathon

  • Association Cardiac troponin-T level and coronary CT findings

    Cardiac troponin-T levels (ng/L), \[electrochemiluminescence (ECLIA) method\]

    Cardiac Troponin-T 0-30 minutes after finishing the Paavo Nurmi Marathon. Control Troponin-T levels and coronary CT angiography at control visit (>30days after marathon).

Study Arms (2)

Under 35 years

Over 44 years

Eligibility Criteria

Age35 Years - 90 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Male participants of the Paavo Nurmi Marathon 2018

You may qualify if:

  • Age under 35 years or over 44 years
  • Participant of Paavo Nurmi Marathon 2018
  • Informed consent signed

You may not qualify if:

  • No informed consent
  • existing coronary artery disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Turku University Hospital, Heart Center

Turku, Finland

Location

MeSH Terms

Conditions

Coronary Artery Disease

Condition Hierarchy (Ancestors)

Coronary DiseaseMyocardial IschemiaHeart DiseasesCardiovascular DiseasesArteriosclerosisArterial Occlusive DiseasesVascular Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

September 21, 2018

First Posted

November 13, 2018

Study Start

August 17, 2018

Primary Completion

December 1, 2022

Study Completion

December 1, 2022

Last Updated

May 8, 2024

Record last verified: 2024-05

Locations

FI(1)