NCT03738592

Brief Summary

Spatial hearing in cochlear implant (CI) users is a challenging investigation field since no studies have explored yet spatial auditory perception in three-dimensional space (3D). Moreover auditory rehabilitation after cochlear implantation is totally devoted to speech rehabilitation to date. A novel methodology based on virtual reality and 3D motion capture protocol in an immersive reality system has recently been developed to evaluate and record spatial hearing abilities of norm-hearing (NH) listeners and CI adults in 3D. The results revealed worse sound localization in 3D for CI users compared to NH participants, and interestingly noted that head movements could improve sound localization performances, leading to a possible track for auditory rehabilitation. The aim of this study is to explore spatial hearing in CI children with the protocol already tested in CI adults. This protocol will be adapted to children over eight years old. Children will have to perform a sound localization task in 3D without any feedback of performances. The knowledge improvement in pediatric sound localization will lead to develop a specific spatial rehabilitation in cochlear implant children.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
36

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jan 2019

Shorter than P25 for not_applicable

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 8, 2018

Completed
1 month until next milestone

First Posted

Study publicly available on registry

November 13, 2018

Completed
2 months until next milestone

Study Start

First participant enrolled

January 24, 2019

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 18, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 18, 2019

Completed
Last Updated

December 19, 2025

Status Verified

December 1, 2025

Enrollment Period

10 months

First QC Date

October 8, 2018

Last Update Submit

December 13, 2025

Conditions

Keywords

spatial hearing perceptioncochlear implantchildvirtual reality

Outcome Measures

Primary Outcomes (1)

  • measure of the spatial hearing deficit matching the distance between the hand pointing error and the sound source position in space

    Data from spatial sound perception will be recorded in three dimensional space (azimuth, elevation, and depth). First, the pointing error will be computed separately for azimuth, elevation, and depth, in terms of constant error (absolute and signed) and variable error. Then, these separate errors will be combined into a cumulative error "D", hence summarizing all three dimensions of space, and taking into account absolute and variable error in one measure.

    thirty minutes

Secondary Outcomes (4)

  • measure of head and eye movements in three dimensional space with a motion tracking system (virtual reality system including a Head-Mounted display) to evaluate their roles in spatial hearing performances.

    thirty minutes

  • impact of age at cochlear implantation on spatial hearing deficit

    thirty minutes

  • change of the pupil diameter during a sound localization task

    thirty minutes

  • correlation between a clinical score (SSQ) and sound localization performances

    28 days

Study Arms (2)

cochlear implant children

EXPERIMENTAL

18 cochlear implant children wil include in this study

Other: behavioral exploration of spatial hearing performancesOther: The Speech, Spatial and Qualities of Hearing Scale (SSQ) questionnaire (for cochlear implant children and their parents)Other: The Speech, Spatial and Qualities of Hearing Scale (SSQ) questionnaire (for parents of CI children)

normal hearing children

OTHER

18 normal hearing children wil include in this study

Other: behavioral exploration of spatial hearing performances

Interventions

Normal hearing children and cochlear implant children will have to localize a sound source in three dimensional space by using a virtual reality system (Neuro immersion platform). The experiment will last thirty minutes. For normal hearing children, this experience will be performed at the inclusion visit. For cochlear implant children, this experience will be performed 28 days (+/- 2 days) after inclusion.

cochlear implant childrennormal hearing children

The SSQ questionnaire for Parents of CI children is composed of three distinct sections (A, B and C). Each section will be filled separately by parents of CI children with one of the study collaborators during 3 telephone calls spaced 1 week apart. Thus, section A will be completed 7 days (+/- 2 days) after inclusion , section B 14 days (+/- 2 days) after inclusion, and section C 21 days (+/- 2 days) after inclusion.

cochlear implant children

For cochlear implant children and their parents, a SSQ questionnaire will be given and completed during the first visit (at the inclusion). This questionnaire offers a version for parents of children with hearing loss ("SSQ Parents CI") and a version for the children themselves ("SSQ Children CI").

cochlear implant children

Eligibility Criteria

Age8 Years - 17 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Age between 8 and 17 included
  • second cochlear implant issued within more than 2 years
  • mean speech recognition over 80% with two cochlear implants
  • normal visual acuity with or without correction
  • abilities to understand experimental instructions
  • a consent form signed by parents or guardian
  • registered with a social security scheme

You may not qualify if:

  • neurologic or psychiatric trouble
  • visual trouble
  • bilateral vestibular areflexia
  • Age between 8 and 17 included
  • normal visual acuity with or without correction
  • abilities to understand experimental instructions
  • a consent form signed by parents or guardian
  • registered with a social security scheme
  • neurologic or psychiatric trouble
  • visual trouble
  • bilateral vestibular areflexia

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Centre de Recherche en Neuroscience de Lyon (CRNL)

Bron, 69676, France

Location

Hôpital Edouard Herriot

Lyon, 69437, France

Location

Related Publications (1)

  • Coudert A, Gaveau V, Gatel J, Verdelet G, Salemme R, Farne A, Pavani F, Truy E. Spatial Hearing Difficulties in Reaching Space in Bilateral Cochlear Implant Children Improve With Head Movements. Ear Hear. 2022 Jan/Feb;43(1):192-205. doi: 10.1097/AUD.0000000000001090.

MeSH Terms

Interventions

Surveys and Questionnaires

Intervention Hierarchy (Ancestors)

Data CollectionEpidemiologic MethodsInvestigative TechniquesHealth Care Evaluation MechanismsQuality of Health CareHealth Care Quality, Access, and EvaluationPublic HealthEnvironment and Public Health

Study Officials

  • Eric TRUY, PUPH

    Hospices Civils de Lyon

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 8, 2018

First Posted

November 13, 2018

Study Start

January 24, 2019

Primary Completion

November 18, 2019

Study Completion

November 18, 2019

Last Updated

December 19, 2025

Record last verified: 2025-12

Locations