NCT03735862

Brief Summary

Investigator will identify a consecutive cohort of patients who have undergone a hiatal hernia repair and are at least 6 months post index procedure.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
85

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jun 2017

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2017

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2018

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2018

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

November 7, 2018

Completed
1 day until next milestone

First Posted

Study publicly available on registry

November 8, 2018

Completed
9 months until next milestone

Results Posted

Study results publicly available

August 5, 2019

Completed
Last Updated

October 1, 2019

Status Verified

September 1, 2019

Enrollment Period

1 year

First QC Date

November 7, 2018

Results QC Date

June 17, 2019

Last Update Submit

September 17, 2019

Conditions

Outcome Measures

Primary Outcomes (1)

  • Number of Subjects Who Required a Revision of the Index Surgery.

    Patient self-report if they had a revision or other laparoscopic surgery following index procedure.

    6-18 months post index procedure

Secondary Outcomes (2)

  • Gastroesophageal Reflux Disease Health Related Quality of Life Score (GERD-HRQL)

    6-18 months post index procedure

  • Medication Use

    6-18 months post index procedure

Other Outcomes (2)

  • Satisfaction With Procedure

    6-18 Months post index procedure

  • Likelihood to Recommend

    6-18 Months post index procedure

Study Arms (1)

Observations Group

Patients who have undergone a hiatal hernia repair with MIROMESH.

Biological: Hepatic derived surgical matrix

Interventions

Hiatal hernia repair with MIROMESH

Also known as: MIROMESH Biologic Matrix
Observations Group

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Had a hiatal hernia repair with MIROMESH greater than 6 months prior to study

You may qualify if:

  • Had a hiatal hernia repair with MIROMESH greater than 6 months prior to study

You may not qualify if:

  • N/A

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Virginia Heartburn and Hernia Institute

Lorton, Virginia, 22079, United States

Location

MeSH Terms

Conditions

Gastroesophageal Reflux

Condition Hierarchy (Ancestors)

Esophageal Motility DisordersDeglutition DisordersEsophageal DiseasesGastrointestinal DiseasesDigestive System Diseases

Limitations and Caveats

This was a retrospectively identified cohort.

Results Point of Contact

Title
Head of Clinical Affairs
Organization
Miromatrix

Study Officials

  • George K Gillian, M.D.

    Virginia Heartburn and Hernia Institute

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 7, 2018

First Posted

November 8, 2018

Study Start

June 1, 2017

Primary Completion

June 1, 2018

Study Completion

October 1, 2018

Last Updated

October 1, 2019

Results First Posted

August 5, 2019

Record last verified: 2019-09

Data Sharing

IPD Sharing
Will not share

Locations