The Effects of Hesperidin on Metabolic Syndrome
Evaluation of the Effects of Hesperidin Supplementation in Patients With Metabolic Syndrome
1 other identifier
interventional
50
1 country
1
Brief Summary
To study the effects of Hesperidin supplement in patients with metabolic syndrome, 50 patients will be randomly allocated to control group or 2 capsules Hesperidin for 12 weeks; both groups will be advised to adherence the investigators' diet and exercise program too. At the first and the end of the intervention, metabolic factors will be assessed and compared between groups.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Jun 2018
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 1, 2018
CompletedFirst Submitted
Initial submission to the registry
October 11, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 1, 2018
CompletedFirst Posted
Study publicly available on registry
November 8, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2018
CompletedNovember 8, 2018
November 1, 2018
5 months
October 11, 2018
November 7, 2018
Conditions
Outcome Measures
Primary Outcomes (1)
Metabolic syndrome: Number of participants with treated metabolic syndrome
number of participants with treated metabolic syndrome
12 weeks
Study Arms (2)
hesperidin
ACTIVE COMPARATORcontrol
PLACEBO COMPARATORInterventions
Eligibility Criteria
You may qualify if:
- Age of 18 to 70 years
- having 3 of 5 of high blood sugar, hypertension, high TG, high waist circumference, low HDL
You may not qualify if:
- pregnancy or lactation
- A history of Cardiovascular disease, Pulmonary disease, Renal disease \& Celiac disease; Cirrhosis
- Following program to lose weight in recent 3 mo
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
National Nutrition and Food Technology Research Institute
Tehran, Iran
Related Publications (1)
Yari Z, Movahedian M, Imani H, Alavian SM, Hedayati M, Hekmatdoost A. The effect of hesperidin supplementation on metabolic profiles in patients with metabolic syndrome: a randomized, double-blind, placebo-controlled clinical trial. Eur J Nutr. 2020 Sep;59(6):2569-2577. doi: 10.1007/s00394-019-02105-2. Epub 2019 Dec 16.
PMID: 31844967DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
October 11, 2018
First Posted
November 8, 2018
Study Start
June 1, 2018
Primary Completion
November 1, 2018
Study Completion
December 1, 2018
Last Updated
November 8, 2018
Record last verified: 2018-11