One Minute Heart Rate Variability Quantification in Airway Obstruction Model
RRV Airway
1 other identifier
interventional
40
0 countries
N/A
Brief Summary
40 healthy volunteers underwent a trial of obstructed breathing through an eighteen cm long, four mm internal diameter tube. Heart rate was recorded during three consecutive sets comprised of one minute control followed by one minute of obstructed breathing, with one minute of rest between sets. Time and frequency domain analysis were used to compare HRV during control versus obstructed breathing.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started May 2015
Shorter than P25 for not_applicable
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 20, 2015
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 11, 2015
CompletedStudy Completion
Last participant's last visit for all outcomes
July 1, 2015
CompletedFirst Submitted
Initial submission to the registry
November 4, 2018
CompletedFirst Posted
Study publicly available on registry
November 7, 2018
CompletedNovember 8, 2018
November 1, 2018
22 days
November 4, 2018
November 6, 2018
Conditions
Outcome Measures
Primary Outcomes (1)
Low Frequency Power Spectral Density
FFT HRV Low Frequency Power Spectral Density
1 minute
Study Arms (1)
Healthy volunteers
EXPERIMENTALHealthy volunteers
Interventions
Heart rate variability analysis extracted from ECG during normal and obstructed breathing
Eligibility Criteria
You may qualify if:
- years old
- healthy
You may not qualify if:
- heart disease
- lung disease
- BMI \> 26
- ECG abnormalities
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (1)
Lehavi A, Golomb N, Leiba R, Katz YS, Raz A. One-minute heart rate variability - an adjunct for airway obstruction identification. Physiol Rep. 2019 Jan;7(1):e13948. doi: 10.14814/phy2.13948.
PMID: 30632302DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- BASIC SCIENCE
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Director of Pediatric Anesthesia
Study Record Dates
First Submitted
November 4, 2018
First Posted
November 7, 2018
Study Start
May 20, 2015
Primary Completion
June 11, 2015
Study Completion
July 1, 2015
Last Updated
November 8, 2018
Record last verified: 2018-11
Data Sharing
- IPD Sharing
- Will not share