Muscle Synergies After Stroke

NCT03731299 | Completed

• 1 other identifier: TVC3
• Study Type: observational
• Target: 114
• Locations: 0 countries
• Sites: N/A

Brief Summary

The aim of this systematic review was to determine the number of muscle synergies and the distribution of muscle weightings in stroke patients during gait.

Conditions

Stroke

Keywords

muscle synergies; gait; functional ability

Outcome Measures

Primary Outcomes (1)

• Amount of muscle synergies derived by non-negative matrix factorization

  Spatial characteristic of muscle synergy compared to healthy adults: the amount of synergies during walking in stroke subjects, the amount of muscles in one synergie and which muscles in one synergy

  Once, in the week of inclusion

Secondary Outcomes (1)

• Distribution of muscle synerigies derived by non-negative matrix factorization

  Once, in the week of inclusion

Study Arms (2)

Stroke

Individuals suffered from a haemorrhagic or ischaemic stroke. Diagnosis has to be confirmed on the basis of CT or MRI imaging.

Healthy adults

Healthy individuals without any neurological or orthopaedic disorder that could influence motor performance and balance

Eligibility Criteria

• Age: 18 Years - 85 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Healthy Volunteers: community sample Stroke: Rehabilitation Hospital RevArte, primary care clinic

You may qualify if:

• haemorrhagic or ischaemic stroke diagnosis, confirmed on the basis of CT or MRI imaging;
• no known history of previous stroke;
• stroke onset within five months; 4 patients are between 18 and 85 years of age;

You may not qualify if:

• A score of 20 or higher on the Trunk Impairment Scale which indicates normal truncal function;
• A score lower than two on the Functional Ambulation Categories (FAC) as patients needed to be able to ambulate without physical support to ensure that gait analysis can be executed safely;
• Not able to sit independently for 30 seconds on a stable surface;
• They suffer from other neurological and orthopaedic disorders that could influence motor performance and balance;
• not able to understand instructions.

Sponsors & Collaborators

• Universiteit Antwerpen: lead

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Steven Truijen, Prof.

  Universiteit Antwerpen

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: October 26, 2018
• First Posted: November 6, 2018
• Study Start: April 1, 2015
• Primary Completion: July 1, 2017
• Study Completion: December 1, 2017
• Last Updated: November 6, 2018

Record last verified: 2018-11

Data Sharing

• IPD Sharing: Will not share