NCT03723629

Brief Summary

In this study, about 2000 GGO patients will be included for a 5-year follow-up. The aim of this study is to elucidate the biological nature of pulmonary GGO lesion and provide evidence for GGO treatment.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
2,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jul 2018

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 27, 2018

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

October 20, 2018

Completed
9 days until next milestone

First Posted

Study publicly available on registry

October 29, 2018

Completed
3.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2022

Completed
Last Updated

October 29, 2018

Status Verified

October 1, 2018

Enrollment Period

3.8 years

First QC Date

October 20, 2018

Last Update Submit

October 26, 2018

Conditions

Lung Cancer

Keywords

Ground glass opacity

Outcome Measures

Primary Outcomes (2)

  • Changes from baseline GGO diameter

    Changes from baseline GGO diameter

    6 months, 1year, 2 years, 3 years, 4 years and 5 years

  • Changes from baseline GGO CT index.

    Changes from baseline GGO CT index.

    6 months, 1year, 2 years, 3 years, 4 years and 5 years

Study Arms (1)

pulmonary GGO

Patients with pulmonary GGO.

Other: No intercention

Interventions

No intercentionOTHER

No intercention

pulmonary GGO

Eligibility Criteria

Age35 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Clinic out patients of thoracic surgery.

You may qualify if:

  • years' old
  • found pulmonary GGO with chest CT scan and CT follow-up after 3 months shows that the GGO remains
  • Diameter of GGO \> 5mm and \< 3cm
  • Solid component of GGO in pulmonary window \< 5mm
  • signed informed consent form

You may not qualify if:

  • receiving immunosuppressor or steriods
  • receiving chemo- or radio- therapy
  • can not receive regular follow-up

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Zhongshan Hospital

Shanghai, Shanghai Municipality, 200032, China

RECRUITING

MeSH Terms

Conditions

Lung Neoplasms

Condition Hierarchy (Ancestors)

Respiratory Tract NeoplasmsThoracic NeoplasmsNeoplasms by SiteNeoplasmsLung DiseasesRespiratory Tract Diseases

Central Study Contacts

Qun Wang

CONTACT

+86-64041990-2018wang.qun@zs-hospital.sh.cn

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 20, 2018

First Posted

October 29, 2018

Study Start

July 27, 2018

Primary Completion

June 1, 2022

Study Completion

June 1, 2022

Last Updated

October 29, 2018

Record last verified: 2018-10

Locations

CN(1)