NCT03713827

Brief Summary

This is a double blinded, split mouth, randomized clinical study that evaluated the performance of a glass hybrid restorative material in non-carious servical lesions in patients with bruxism. The lesions were restored with glass hybrid restorative (Equia Forte) or nano ceramic composite resin (Ceram-x One). Restorations were evaluated after 24 months according to USPHS criteria and the data were evaluated.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
25

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Mar 2016

Longer than P75 for not_applicable

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2016

Completed
2.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2018

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

October 15, 2018

Completed
7 days until next milestone

First Posted

Study publicly available on registry

October 22, 2018

Completed
3.5 years until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2022

Completed
Last Updated

October 22, 2018

Status Verified

October 1, 2018

Enrollment Period

2.3 years

First QC Date

October 15, 2018

Last Update Submit

October 18, 2018

Conditions

Keywords

glass hybridsbruxismNon carious cervical lesions

Outcome Measures

Primary Outcomes (1)

  • Retention Alpha for at least 90% of the restorations

    The primary factor for determining the clinical performance of a restorative material is the retention rate. It represents the survival rates of the restorations after a period of time. According to ADA guidelines, a restorative material should show at leat 90% alpha retention rate after 18 months to be considered as clinically acceptable. The retention is assesed as alpha (retentive restoratation) or charlie (failed restoration). Clinical evaluation is performed to examine if the restoration is in place or has fallen.

    24 months

Secondary Outcomes (1)

  • marginal adaptation score alpha

    24 months

Study Arms (2)

"composite resin", "Ceram-x One Universal"

ACTIVE COMPARATOR

tooth restoration with nano-ceramic composite resin "Ceram-x one Universal"

Device: tooth restoration

"glass ionomer cement", "Equia Forte"

ACTIVE COMPARATOR

Tooth restoration with glass ionomer cement (Glass hybrid restorative system) "Equia Forte"

Device: tooth restoration

Interventions

restoration of non carious cervical lesions with two different restorative materials

"composite resin", "Ceram-x One Universal""glass ionomer cement", "Equia Forte"

Eligibility Criteria

Age42 Years - 72 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • non-hospitalized, healthy patients that were seeking dental treatmen
  • occlusally contacted teeth

You may not qualify if:

  • Patients having intensive medical history
  • Chronic periodontitis,
  • high caries activity,
  • extremely poor oral hygiene,
  • teeth with restorations,
  • mobility due to periodontal disease
  • in contacted with removable prosthetic construction were excluded from the study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Bruxism

Condition Hierarchy (Ancestors)

Tooth DiseasesStomatognathic DiseasesHabitsBehavior

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
FACTORIAL
Model Details: double blinded, split mouth, randomized clinical trial
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
principal investigator

Study Record Dates

First Submitted

October 15, 2018

First Posted

October 22, 2018

Study Start

March 1, 2016

Primary Completion

June 1, 2018

Study Completion

May 1, 2022

Last Updated

October 22, 2018

Record last verified: 2018-10