NCT03711526

Brief Summary

6-minute walk test (6MWT) is widely used in cardiopulmonary surgery as a prognostic marker. This prospective cohort study aims to find whether 6MWT will be a good prognostic factor for patients who will undergo laparoscopic gastrointestinal surgery.The investigators will enroll patients awaiting elective laparoscopic gastrointestinal surgery in this study. After informed consent was obtained, the participants will be evaluated through 6MWT. Preoperative assessment and conditions during operation will be recorded. The investigators will analyze the correlation between preoperative 6MWT's result and outcomes after laparoscopic gastrointestinal surgery.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
200

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2019

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 10, 2018

Completed
8 days until next milestone

First Posted

Study publicly available on registry

October 18, 2018

Completed
3 months until next milestone

Study Start

First participant enrolled

January 1, 2019

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2019

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 31, 2020

Completed
Last Updated

July 16, 2019

Status Verified

May 1, 2019

Enrollment Period

12 months

First QC Date

October 10, 2018

Last Update Submit

July 13, 2019

Conditions

Outcome Measures

Primary Outcomes (1)

  • Postoperative complications

    Postoperative complications includes postoperative wound infections, delayed union or nonunion, intraperitoneal abscesses, intestinal obstruction, anastomotic fistula, postoperative hemorrhage which need blood transfusion, pulmonary complications, cardiovascular complications, cerebrovascular complications, thrombotic events, acute liver failure or deterioration of liver function, acute renal failure or deterioration of renal function, urinary infection, gastrointestinal hemorrhage, postoperative delirium, et al.

    30 days

Secondary Outcomes (4)

  • Mortality rate

    30 days

  • Second operation without plan

    30 days after surgery

  • Rehospitalized

    30 days

  • Patient satisfaction

    30 days

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Inpatient from 18 y/o to 75 y/o going to have elective laparoscopic gastrointestinal surgery in Peking Union Medical College Hospital from January 2019 to December 2019.

You may qualify if:

  • Inpatient in Peking Union Medical College Hospital from January 2019 to December 2019
  • From 18 y/o to 75 y/o
  • Consent got from patients
  • Decide to take the elective laparoscopic gastrointestinal surgery in Peking Union Medical College Hospital

You may not qualify if:

  • Refuse to take part in the study (due to any reason)
  • ASA grade ≥ IV
  • Unable to cooperate with the study (mental disorder, disturbance of consciousness, dysnoesia)
  • Have developed unstable angina or myocardial infarction in the recent 6 months
  • HR\>120 beats/min or SBP\>180mm/Hg or DBP\>100mmHg at resting state
  • During acute episode of asthma
  • Diseases cause severe limitation of walking, including severe lumbar spondylosis, knee osteoarthritis, lower extremity varicose veins, et al.
  • Other conditions make patients can't cooperate with 6MWT

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Peking Union Medical College Hospital

Beijing, Beijing Municipality, 100730, China

RECRUITING

Related Publications (1)

  • Liu Y, Liu Z, Zhang L, Zhang Y, Zhang N, Han Y, Shen L. Preoperative 6-minute walk distance is associated with postoperative complications in patients undergoing laparoscopic gastrointestinal cancer surgery. Eur J Surg Oncol. 2024 Jan;50(1):107139. doi: 10.1016/j.ejso.2023.107139. Epub 2023 Nov 4.

Study Officials

  • YUGUANG HUANG, MD.

    Peking Union Medical College Hospital, Chinese Academy of Medicine Sciences

    PRINCIPAL INVESTIGATOR

Central Study Contacts

ZIJIA LIU, M.D.

CONTACT

YUGUANG HUANG, M.D.

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 10, 2018

First Posted

October 18, 2018

Study Start

January 1, 2019

Primary Completion

December 31, 2019

Study Completion

March 31, 2020

Last Updated

July 16, 2019

Record last verified: 2019-05

Locations