NCT03711461

Brief Summary

the investigator aimed to observe the changes and difference of pharyngeal function parameters between the patients receiving the intubated or nonintubated thoracoscopy by esophageal manometry, impedance, and ultrasonography

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
32

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Nov 2018

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 11, 2018

Completed
7 days until next milestone

First Posted

Study publicly available on registry

October 18, 2018

Completed
15 days until next milestone

Study Start

First participant enrolled

November 2, 2018

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 25, 2020

Completed
3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

October 25, 2023

Completed
Last Updated

September 18, 2019

Status Verified

October 1, 2018

Enrollment Period

2 years

First QC Date

October 11, 2018

Last Update Submit

September 16, 2019

Conditions

Outcome Measures

Primary Outcomes (1)

  • impedance changes

    using esophageal manometry to evaluate the swallowing

    average 4 hours

Secondary Outcomes (2)

  • esophageal pressure changes

    average 4 hours

  • hyoid bone distance

    average 4 hours

Study Arms (2)

nonintubated

ACTIVE COMPARATOR

patients received nonintubated during thoracoscopy

Device: nonintubated

intubated

EXPERIMENTAL

patients receiving intubated during thoracoscopy

Device: endotracheal tube (double lumen)

Interventions

patients routinely use double lumen endotracheal intubation while they have received thoracoscopy

intubated

patients receiving nonintubated anesthetic plan while they have received thoracoscopy

nonintubated

Eligibility Criteria

Age20 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients who fulfill the criteria of nonintubated thoracoscopy under general anesthesia, including tumours smaller than 6 cm, peripheral lesions, no evidence of severe adhesion; and no evidence of chest wall, diaphragm, or main bronchus involvement. Patients who had potential or confirmed airway complications such as bronchial tumor or hemothorax, morbid obesity (BMI greater than 35 kg·m-2), coagulopathy, anatomical deformity or an American Society of Anesthesiology (ASA) classification greater than 3 were excluded
  • Aged from 20-80 years old

You may not qualify if:

  • Major systemic disease, such as congestive heart failure, liver cirrhosis, and end stage renal disease.
  • Patients who have the risk of difficult ventilation or intubation.
  • pregnant women
  • coagulopathy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ya-Jung Cheng

Taipei, 10002, Taiwan

RECRUITING

Study Officials

  • Ya-Jung Cheng, MD

    National Taiwan University Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Ya-Jung Cheng, MD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
the swallowing function assessor is blind
Purpose
OTHER
Intervention Model
PARALLEL
Model Details: intubated and nonintubated patients
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 11, 2018

First Posted

October 18, 2018

Study Start

November 2, 2018

Primary Completion

October 25, 2020

Study Completion

October 25, 2023

Last Updated

September 18, 2019

Record last verified: 2018-10

Locations