Endocannabinoid and Psychological Responses to Yoga in Healthy Adults

NCT03710577 | Completed Results

• 3 other identifiers: 2017-0980A176000EDUC/KINESIOLOGY/KINESIO
• Study Type: interventional
• Target: 12
• Locations: 1 country
• Sites: 1

Brief Summary

This study evaluates the acute effect of yoga on plasma levels of endocannabinoids and mood (i.e., mood disturbance, anxiety, pain) compared to one session of quiet rest. Participants completed one session of yoga and one session of quiet rest on two separate days.

Conditions

Healthy

Outcome Measures

Primary Outcomes (2)

• Change in Plasma Concentration of N-arachidonoylethanolamine

  Plasma concentration of anandamide, one effector of the endocannabinoid system

  This will be measured 2 times during each study visit, once before the assigned study task (i.e., baseline) and once upon task completion (i.e., approx. 40 min. later)

• Change in Plasma Concentration of 2-Arachidonoylglycerol (2-AG)

  Plasma concentration of 2-AG, one effector of the endocannabinoid system

  This will be measured 2 times during each study visit, once before the assigned study task (i.e., baseline) and once upon task completion (i.e., approx. 40 min. later)

Secondary Outcomes (3)

• Change in Total Mood Disturbance as Measured by the Profile of Mood States

  This will be measured 2 times during each study visit, once before the assigned study task (i.e., baseline) and once upon task completion (i.e., approx. 40 min. later)

• Change in State Anxiety as Measured by the State-Trait Anxiety Inventory

  This will be measured 2 times during each study visit, once before the assigned study task (i.e., baseline) and once upon task completion (i.e., approx. 40 min. later)

• Change in Total Pain as Measured by the Short-form McGill Pain Questionnaire

  This will be measured 2 times during each study visit, once before the assigned study task (i.e., baseline) and once upon task completion (i.e., approx. 40 min. later)

Study Arms (2)

Yoga

EXPERIMENTAL

40 minutes of Vinyasa yoga

Behavioral: Yoga

Quiet Rest

PLACEBO COMPARATOR

40 minutes of quiet rest

Behavioral: Quiet Rest

Interventions

Yoga BEHAVIORAL

1 session

Yoga

Quiet Rest BEHAVIORAL

1 session

Quiet Rest

Eligibility Criteria

• Age: 18 Years - 45 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• greater than or equal to 18 years old and \< 45 years old and
• report being healthy.

You may not qualify if:

• Being pregnant or planning to become pregnant,
• currently smoking,
• having a history of light headedness or fainting during blood draws or physical activity,
• having a history of chest pain during physical activity,
• having a bone, joint, cardiac, or other medical condition that a doctor has said may be worsened by physical activity,
• taking medications for any chronic diseases such as high blood pressure or diabetes,
• responding 'Yes' to any of the seven questions on the Par-Q.

Sponsors & Collaborators

• University of Wisconsin, Madison: lead

Study Sites (1)

University of Wisconsin-Madison Natatorium

Madison, Wisconsin, 53706, United States

Location

MeSH Terms

Interventions

Yoga

Intervention Hierarchy (Ancestors)

Mind-Body Therapies; Complementary Therapies; Therapeutics; Spiritual Therapies; Exercise Movement Techniques; Physical Therapy Modalities

Results Point of Contact

• Title: Dr. Kelli Koltyn
• Organization: Univerisity of Wisconsin-Madison

koltyn@education.wisc.edu

608-262-4234

Study Officials

• Kelli Koltyn, PhD

  University of Wisconsin, Madison

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: Yes

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: The proposed study is an acute, single group, crossover pilot study where participants will complete control and experimental conditions.

Study Record Dates

• First Submitted: June 21, 2018
• First Posted: October 18, 2018
• Study Start: December 12, 2017
• Primary Completion: May 16, 2018
• Study Completion: May 16, 2018
• Last Updated: December 8, 2020
• Results First Posted: October 26, 2020

Record last verified: 2020-11

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)