Menstrual Cycle Phases on Recovery and Cognitive Function

NCT03708692 | Completed

• 1 other identifier: Menstruel Cycle Recovery
• Study Type: observational
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study was to investigate the effects of menstrual cycle phases on recovery and cognitive function after general anesthesia.

Conditions

Menstrual Cycle; Cognitive Function; Recovery; General Anesthesia

Keywords

General Anesthesia; Recovery; Cognitive Function; Menstrual Cycle phase

Outcome Measures

Primary Outcomes (1)

• Cognitive function

  After general anesthesia, the time of return of the behaviors such as opening the eyes, fulfilling the orders or saying the age will be recorded and evaluated as the recovery criteria. In the postop recovery period, the patient will be subjected to mini mental state testing (MMST) and cognitive functions will be evaluated.

  1 month

Study Arms (2)

Group F

Patients with menstrual cycle between 8-12 days were called Group F (Follicular phase)

Behavioral: Group F

Group L

Patients with menstrual cycle between 20-24 were called Group L (Luteal phase)

Behavioral: Group F

Interventions

Group F BEHAVIORAL

After general anesthesia, the time of return of the behaviors such as opening the eyes, fulfilling the orders or saying the age will be recorded and evaluated as the recovery criteria. In the postop recovery period, the patient will be subjected to mini mental state testing (MMST) and cognitive functions will be evaluated.

Also known as: Group L

Group F; Group L

Eligibility Criteria

• Age: 18 Years - 45 Years
• Gender Eligibility Details: The study is performed on female gender with menstrual cycle.
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

Current study is performed on female gender with reguler menstrual cycle, who were accepted to participate in the study,

You may qualify if:

• The study included 80 women with ASA I-II,
• Aged 18 to 45 years, who were accepted to participate in the study,
• were smoking,
• did not use oral contraceptives,
• had no menstrual irregularity (regular 28 ± 2 days menstrual cycle)

You may not qualify if:

• In preop evaluation patients had difficulties in communication,
• amenorrhea,
• pregnancy,
• delirium,
• psychological illness,
• major depressive disorder,
• patients with a history of acute illness (such as in intensive care unit follow-up),
• which may affect cognitive function and daily life activities in the last 6 months,
• malignancy,
• acute renal failure,
• substance abuse and patients older than 45 years and male sex will be excluded from the study.

Sponsors & Collaborators

• Yuzuncu Yil University: lead

Study Sites (1)

Van yuzuncu Yıl University, Dursun Odabas Medical Center

Van, 65080, Turkey (Türkiye)

Location

Study Officials

• Nureddin Yuzkat, Assist Prof

  Yuzuncu Yil University

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assist. Prof

Study Record Dates

• First Submitted: October 13, 2018
• First Posted: October 17, 2018
• Study Start: September 30, 2018
• Primary Completion: November 30, 2018
• Study Completion: December 1, 2018
• Last Updated: February 7, 2020

Record last verified: 2020-02

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)