NCT03706651

Brief Summary

The purpose of the study is to determine whether tele-expertise would be more effective and more cost-effective for the Interpretation of MRI Among Neonates with high risk of neurological sequelae

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
70

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jan 2014

Longer than P75 for all trials

Geographic Reach
1 country

4 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2014

Completed
3.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2017

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2018

Completed
9 months until next milestone

First Submitted

Initial submission to the registry

September 24, 2018

Completed
22 days until next milestone

First Posted

Study publicly available on registry

October 16, 2018

Completed
Last Updated

October 16, 2018

Status Verified

September 1, 2018

Enrollment Period

3.8 years

First QC Date

September 24, 2018

Last Update Submit

October 10, 2018

Conditions

Outcome Measures

Primary Outcomes (1)

  • Time between MRI and decision of intensive care continuation

    A cerebral MRI for neonates, prescribed by the ICU team, will be performed, requiring a specialist advice. This advice is mandatory for ICU team to decide the intensive care continuation.

    1 week after discharge

Secondary Outcomes (2)

  • Time between MRI and the specialist report

    1 week after discharge

  • Time between MRI and the discussions with the parents

    1 week after discharge

Study Arms (2)

Exposed group, during Tele-expertise

Infants hospitalized in health facilities performing tele-expertise

Device: Infants hospitalized in health facilities performing Tele-expertise

Exposed group, Prior Tele-expertise

Infants hospitalized in health facilities performing Tele-expertise prior implementation of Tele-expertise

Interventions

Eligibility Criteria

AgeUp to 28 Days
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)
Sampling MethodNon-Probability Sample
Study Population

Infants hospitalized in neonatology unit

You may qualify if:

  • Less than 28 days of life
  • Mandatory to have a medical advice in paediatric neuroradiology for interpretation of brain MRI

You may not qualify if:

  • None

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (4)

Service de radiopédiatrie

Le Kremlin-Bicêtre, 94275, France

Location

Service de Radiopédiatrie. Hôpital Trousseau

Paris, 75012, France

Location

Service de radiopédiatrie. Hôpital Necker

Paris, 75015, France

Location

Service de radiopédiatrie - Hôpital Robert Debré

Paris, 75019, France

Location

Related Publications (2)

  • Larroque B, Ancel PY, Marret S, Marchand L, Andre M, Arnaud C, Pierrat V, Roze JC, Messer J, Thiriez G, Burguet A, Picaud JC, Breart G, Kaminski M; EPIPAGE Study group. Neurodevelopmental disabilities and special care of 5-year-old children born before 33 weeks of gestation (the EPIPAGE study): a longitudinal cohort study. Lancet. 2008 Mar 8;371(9615):813-20. doi: 10.1016/S0140-6736(08)60380-3.

    PMID: 18328928BACKGROUND
  • Kidholm K, Ekeland AG, Jensen LK, Rasmussen J, Pedersen CD, Bowes A, Flottorp SA, Bech M. A model for assessment of telemedicine applications: mast. Int J Technol Assess Health Care. 2012 Jan;28(1):44-51. doi: 10.1017/S0266462311000638.

    PMID: 22617736BACKGROUND

Related Links

MeSH Terms

Conditions

Hypoxia, Brain

Condition Hierarchy (Ancestors)

Brain DiseasesCentral Nervous System DiseasesNervous System DiseasesHypoxiaSigns and Symptoms, RespiratorySigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Elisabeth Dion, MD, PhD

    Centre de téléradiologie, Assistance Publique, Hôpitaux de Paris

    PRINCIPAL INVESTIGATOR
  • Isabelle Durand-Zaleski, MD, PhD

    DRCD URC Eco. Assistance Publique - Hôpitaux de Paris

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 24, 2018

First Posted

October 16, 2018

Study Start

January 1, 2014

Primary Completion

October 1, 2017

Study Completion

January 1, 2018

Last Updated

October 16, 2018

Record last verified: 2018-09

Locations