NCT03706066

Brief Summary

The purpose of this Post Marketing Study is to study the safety and effectiveness of the ACRYSOF IQ PanOptix intraocular lens (IOL) in an Indian population.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
80

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jan 2019

Shorter than P25 for all trials

Geographic Reach
1 country

5 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 11, 2018

Completed
4 days until next milestone

First Posted

Study publicly available on registry

October 15, 2018

Completed
3 months until next milestone

Study Start

First participant enrolled

January 15, 2019

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 18, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 18, 2020

Completed
Last Updated

February 5, 2020

Status Verified

February 1, 2020

Enrollment Period

1 year

First QC Date

October 11, 2018

Last Update Submit

February 4, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Best corrected binocular visual acuity at distance (4 m) at 3 months post bilateral implantation

    Visual acuity will be assessed using Early Treatment Diabetic Retinopathy Study (ETDRS) charts and reported in logarithm minimum angle of resolution (logMAR).

    Month 3 (following second eye surgery)

Study Arms (1)

PanOptix

Cataract surgery with implantation of Acrysof IQ PanOptix IOL

Device: Acrysof IQ PanOptix IOLProcedure: Cataract surgery

Interventions

Single-piece, ultraviolet and blue-light filtering, foldable, multifocal intraocular lens (IOL) inserted into the capsular bag during cataract surgery

Also known as: Model TFNT00
PanOptix

Per investigator's standard of care

PanOptix

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

This study will enroll males and females who are at least 18 years of age or older at the time of screening, have no ocular pathology that could confound study outcomes, have been advised bilateral cataract extraction, and desire an intraocular lens (IOL) that provides the potential for correction of near, intermediate, and distance vision.

You may qualify if:

  • Able to comprehend and willing to sign informed consent and complete all required postoperative follow-up procedures;
  • Advised cataract extraction in both eyes and agreed for bilateral implantation of ACRYSOF IQ PanOptix lens;
  • Preoperative regular keratometric astigmatism of ≤1.0 D in both eyes.

You may not qualify if:

  • Pregnant or lactating, current or planned, during the course of the study;
  • Retinal abnormalities (Macular Degeneration, dystrophy, edema , traction or other pathologies affecting vision);
  • Clinically significant corneal abnormalities;
  • History of retinal conditions;
  • Previous refractive surgery, including LASIK;
  • Glaucoma;
  • Any condition that may not be appropriate to this study, as per the Investigator's expert medical opinion.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (5)

Alcon Investigative Site

Ahmedabad, Gujarat, 380052, India

Location

Alcon Investigative Site

Chennai, Tamil Nadu, 600006, India

Location

Alcon Investigative Site

Coimbatore, Tamil Nadu, 641002, India

Location

Alcon Investigative Site

Bangalore, 560010, India

Location

Alcon Investigative Site

Hyderabad, 500034, India

Location

MeSH Terms

Conditions

Cataract

Interventions

Cataract Extraction

Condition Hierarchy (Ancestors)

Lens DiseasesEye Diseases

Intervention Hierarchy (Ancestors)

Refractive Surgical ProceduresOphthalmologic Surgical ProceduresSurgical Procedures, Operative

Study Officials

  • Study Director

    Alcon Laboratories (India) PVT.LTD

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 11, 2018

First Posted

October 15, 2018

Study Start

January 15, 2019

Primary Completion

January 18, 2020

Study Completion

January 18, 2020

Last Updated

February 5, 2020

Record last verified: 2020-02

Data Sharing

IPD Sharing
Will not share

Locations