The Impact of Physical Activity on the Postoperative Symptoms, Complications, and Quality of Life Among Lung Cancer

NCT03705546 | Active Not Recruiting

• 1 other identifier: SMC 2015-11-025-002(C)
• Study Type: observational
• Target: 1,050
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to examine the impact of physical activity on the postoperative symptoms, complication, and quality of life.

Conditions

Lung Neoplasms

Outcome Measures

Primary Outcomes (1)

• The change of quality of life: (EORTC QLQ) core30 (C30)

  The change of quality of life is measured using the European Organization for Research Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ) core30 (C30). The scale for quality of life is transformed into a score from 0 to 100, derived by 4-point Likert scale. A higher score represents a higher level of quality of life.

  Before surgery (baseline), and 1, 6, 12, 24, 36, 48, and 60 months after surgery

Secondary Outcomes (2)

• Postoperative pulmonary complications

  Within 30 days after surgery

• The change of symptom

  Before surgery (baseline), and 1, 6, 12, 24, 36, 48, and 60 months after surgery

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

The study population in this study consists of patients who are diagnosed with lung cancer and scheduled for surgery in a lung cancer center at Seoul.

You may qualify if:

• Patients who are diagnosed with lung cancer
• Patients who are able to walk with ECOG (Eastern Cooperative Oncology Group) performance status \< 1
• Patients who understand the purpose of this study and provide the written informed consent

You may not qualify if:

• Patients who have difficulty for walking
• Patients with history of other cancer in the last 3 years
• Patients with neoadjuvant chemotherapy and/or radiation therapy
• Patients who are diagnosed with recurrent lung cancer or multiple cancer
• Foreigner of patients from overseas who are not able regularly participate in this study

Sponsors & Collaborators

• Samsung Medical Center: lead

Study Sites (1)

Samsung Medical Center

Seoul, 06351, South Korea

Location

Related Publications (3)

• Kong S, Shin S, Jeon YJ, Lee G, Cho JH, Kim HK, Shim YM, Cho J, Kang D, Park HY. Factors associated with failure of cardiopulmonary function recovery after lung cancer surgery. Respirology. 2023 Nov;28(11):1060-1068. doi: 10.1111/resp.14581. Epub 2023 Aug 29.

  PMID: 37642118 DERIVED

• Shin S, Kong S, Kang D, Lee G, Cho JH, Shim YM, Cho J, Kim HK, Park HY. Longitudinal changes in pulmonary function and patient-reported outcomes after lung cancer surgery. Respir Res. 2022 Aug 30;23(1):224. doi: 10.1186/s12931-022-02149-9.

  PMID: 36042472 DERIVED

• Lee H, Kim HK, Kang D, Kong S, Lee JK, Lee G, Shin S, Cho J, Zo JI, Shim YM, Park HY. Prognostic Value of 6-Min Walk Test to Predict Postoperative Cardiopulmonary Complications in Patients With Non-small Cell Lung Cancer. Chest. 2020 Jun;157(6):1665-1673. doi: 10.1016/j.chest.2019.12.039. Epub 2020 Jan 25.

  PMID: 31987880 DERIVED

MeSH Terms

Conditions

Lung Neoplasms

Condition Hierarchy (Ancestors)

Respiratory Tract Neoplasms; Thoracic Neoplasms; Neoplasms by Site; Neoplasms; Lung Diseases; Respiratory Tract Diseases

Study Officials

• Hong Kwan Kim, Ph.D.

  Samsung Medical Center

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 5, 2018
• First Posted: October 15, 2018
• Study Start: March 4, 2016
• Primary Completion: December 31, 2020
• Study Completion: March 3, 2026
• Last Updated: May 24, 2024

Record last verified: 2024-05

Data Sharing

• IPD Sharing: Will not share

Locations

KR (1)