NCT03704389

Brief Summary

The risks and benefits of many diagnostic approaches and treatments differ for older adults compared to middle aged adults. When diagnostic and therapeutic strategies are misapplied to older adults this can lead to increased morbidity and mortality. Well established examples where clinicians do not often follow best practices in the care of older adults include those identified by the American Geriatrics Society for the Choosing Wisely initiative: 1) testing and treatment for asymptomatic bacteriuria, 2) prostate specific antigen testing in older men without prostate cancer, and 3) overuse of insulin or oral hypoglycemics for type 2 diabetes. Clinical decision support nudges, informed by social psychology and delivered via electronic health records (EHRs), are promising strategies to reduce the misuse of services in cases where optimal utilization may not be zero but should be well below current practice. These interventions seek to influence conscious and unconscious drivers of clinical decision making, are low cost to implement and disseminate, and can be incorporated into existing delivery systems. In the R21 phase of this Behavioral Economics Applications to Geriatrics Leveraging EHRs (BEAGLE) study, we will: select EHR delivered nudges to address 3 topics of potential misuse in older adults based on the main psychological drivers of overuse identified in interviews with high-using clinicians; develop and pilot test decision support tools within a health systems' EHR to understand technical feasibility, work flow fit, preliminary impact on clinical outcomes, and clinician acceptability; and develop and validate electronic clinical quality measures of potential overuse/misuse related to the care of older adults.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
664

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jan 2019

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 9, 2018

Completed
3 days until next milestone

First Posted

Study publicly available on registry

October 12, 2018

Completed
3 months until next milestone

Study Start

First participant enrolled

January 17, 2019

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 17, 2019

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

August 18, 2019

Completed
6.1 years until next milestone

Results Posted

Study results publicly available

October 7, 2025

Completed
Last Updated

October 7, 2025

Status Verified

September 1, 2025

Enrollment Period

6 months

First QC Date

October 9, 2018

Results QC Date

July 18, 2022

Last Update Submit

September 18, 2025

Conditions

Keywords

GeriatricsClinical decision supportBehavioral Economics

Outcome Measures

Primary Outcomes (3)

  • Misuse of Urinalysis or Urine Culture in Older Women

    Percentage of women patients aged 65 years and older who underwent a urinalysis and/or urine culture for suspected urinary tract infection (UTI) who did not have genitourinary specific symptoms

    6 months intervention period

  • Prostate-Specific Antigen (PSA) Testing in the Elderly

    Percent of male patients seen by participating clinicians 76 and older with no history of prostate cancer who had a PSA test done during the measurement period

    6 month intervention period

  • Diabetes Overtreatment in the Elderly

    Percent of diabetes patients 75 and older treated with insulin or oral hypoglycemic with hemoglobin A1c less than 7.0.

    6 month intervention period

Study Arms (1)

Clinical decision support intervention

EXPERIMENTAL

Participating clinicians will receive any of three clinical decision support nudges within the electronic health record when all eligibility criteria are met within a patient's chart.

Behavioral: Clinical decision support

Interventions

Clinical decision support nudges within the electronic health record

Clinical decision support intervention

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Northwestern Medicine primary care clinician caring for adults
  • Provides informed consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Northwestern Medicine

Chicago, Illinois, 60611, United States

Location

MeSH Terms

Conditions

Diabetes Mellitus, Type 2

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Results Point of Contact

Title
Stephen D. Persell, MD, MPH, FACP
Organization
Northwestern University

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 9, 2018

First Posted

October 12, 2018

Study Start

January 17, 2019

Primary Completion

July 17, 2019

Study Completion

August 18, 2019

Last Updated

October 7, 2025

Results First Posted

October 7, 2025

Record last verified: 2025-09

Data Sharing

IPD Sharing
Will not share

Locations