NCT03697213

Brief Summary

This study investigates the use of the Surprise Question \[SQ\] (would you be surprised if this patient were to die in the next 12 months?) in routine practice. In particular, the study will investigate the consistency of the responses to the SQ and the relationship with the subsequent course of action decided upon.

Trial Health

93
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
250

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Mar 2019

Shorter than P25 for all trials

Geographic Reach
6 countries

6 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 25, 2018

Completed
10 days until next milestone

First Posted

Study publicly available on registry

October 5, 2018

Completed
6 months until next milestone

Study Start

First participant enrolled

March 25, 2019

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2020

Completed
Last Updated

March 27, 2020

Status Verified

March 1, 2020

Enrollment Period

11 months

First QC Date

September 25, 2018

Last Update Submit

March 25, 2020

Conditions

Palliative CareTerminal Illness

Keywords

Surprise QuestionPrognostication

Outcome Measures

Primary Outcomes (1)

  • Probability estimate

    The continuous estimate of probability of dying within the next 12 months for the SQ (0-100%).

    Participants will have up to 8 months (until the study closes) to provide an estimate for each vignette (n=20)

Secondary Outcomes (3)

  • The Surprise Question

    up to 8 months (until the study closes)Participants will have up to 8 months (until the study closes) to provide a response for each vignette (n=20)

  • The alternative Surprise Question

    up to 8 months (until the study closes)Participants will have up to 8 months (until the study closes) to provide a response for each vignette (n=20)

  • Treatment options

    up to 8 months (until the study closes)Participants will have up to 8 months (until the study closes) to provide a response for each vignette (n=20)

Study Arms (1)

General Practitioners

Registered General Practitioners in one of the six participating countries.

Other: Online study

Interventions

Online studyOTHER

20 hypothetical patient summaries

General Practitioners

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

A convenience sample of registered General Practitioners (GPs) with a variety of years of experience and seniority across six European countries will be approached to participate

You may qualify if:

  • Registered General Practitioner in one of the six participating countries
  • Able to read and understand the language in which the questionnaire is presented to them

You may not qualify if:

  • None

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (6)

University of Antwerp

Antwerp, Belgium

Location

University of Mainz

Mainz, Germany

Location

University of Bologna

Bologna, Italy

Location

Radboud University Medical Centre

Nijmegen, Netherlands

Location

University Hospital of Bern

Bern, Switzerland

Location

Marie Curie Palliative Care Research Department

London, W1W 7EJ, United Kingdom

Location

Related Publications (2)

  • White N, Oostendorp LJ, Vickerstaff V, Gerlach C, Engels Y, Maessen M, Tomlinson C, Wens J, Leysen B, Biasco G, Zambrano S, Eychmuller S, Avgerinou C, Chattat R, Ottoboni G, Veldhoven C, Stone P. An online international comparison of palliative care identification in primary care using the Surprise Question. Palliat Med. 2022 Jan;36(1):142-151. doi: 10.1177/02692163211048340. Epub 2021 Oct 1.

    PMID: 34596445DERIVED

  • White N, Oostendorp L, Vickerstaff V, Gerlach C, Engels Y, Maessen M, Tomlinson C, Wens J, Leysen B, Biasco G, Zambrano S, Eychmuller S, Avgerinou C, Chattat R, Ottoboni G, Veldhoven C, Stone P. An online international comparison of thresholds for triggering a negative response to the "Surprise Question": a study protocol. BMC Palliat Care. 2019 Apr 9;18(1):36. doi: 10.1186/s12904-019-0413-x.

    PMID: 30979361DERIVED

Related Links

Study Officials

  • Patrick Stone, MA, MD, FRCP

    University College, London

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 25, 2018

First Posted

October 5, 2018

Study Start

March 25, 2019

Primary Completion

March 1, 2020

Study Completion

March 1, 2020

Last Updated

March 27, 2020

Record last verified: 2020-03

Locations

GB(1)BE(1)DE(1)CH(1)NL(1)IT(1)