NCT03687736

Brief Summary

An interventional Phase 4 study to assess subject satisfaction with abobotulinumtoxinA treatment.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
120

participants targeted

Target at P50-P75 for phase_4

Timeline
Completed

Started Oct 2018

Geographic Reach
1 country

6 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 19, 2018

Completed
8 days until next milestone

First Posted

Study publicly available on registry

September 27, 2018

Completed
5 days until next milestone

Study Start

First participant enrolled

October 2, 2018

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 7, 2019

Completed
27 days until next milestone

Study Completion

Last participant's last visit for all outcomes

December 4, 2019

Completed
4 months until next milestone

Results Posted

Study results publicly available

March 18, 2020

Completed
Last Updated

August 26, 2022

Status Verified

March 1, 2020

Enrollment Period

1.1 years

First QC Date

September 19, 2018

Results QC Date

February 18, 2020

Last Update Submit

August 24, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Subject Satisfaction When Treated With abobutulinumtoxinA in Their Glabellar Lines

    Percentage of subjects satisfied with the treatment results assessed by satisfaction question at Month 12 visit.

    12 months

Secondary Outcomes (6)

  • Subject Satisfaction With Aesthetic Outcome in Treated Area

    Months 1,3,6,7,9 and 12

  • Evaluate Subject Satisfaction; Appraisal of Lines - Between Eyebrows

    Months 1,3,6,7,9 and 12

  • Evaluate the Impact of Treatment; Psychological Function

    Months 1,3,6,7,9 and 12

  • Subject Self-Assessment Using a 4-point Categorical Scale

    Months 1,3,6,7,9 and 12

  • Investigator Live Assessment Using a 4-point Photographic Scale of Glabellar Line Severity

    Months 1,3,6,7,9 and 12

  • +1 more secondary outcomes

Study Arms (1)

AbobotulinumtoxinA

OTHER

Open-label

Biological: AbobotulinumtoxinA

Interventions

AbobotulinumtoxinA treatment in the glabellar region at Baseline and Month 6

AbobotulinumtoxinA

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Moderate to Severe Glabellar Lines at Maximum Frown
  • Understands study requirements and signs an informed consent

You may not qualify if:

  • Known allergy to any component of study product
  • Pregnant or breast feeding or intending to get pregnant during the study
  • Botulinum toxin treatment in the face within 9 months

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (6)

Galderma Study Site

Los Angeles, California, 90025, United States

Location

Galderma Study Site

San Francisco, California, 94115, United States

Location

Galderma Study Site

Santa Monica, California, 90404, United States

Location

Galderma Study Site

Greenwood Village, Colorado, 80111, United States

Location

Galderma Study Site

Chicago, Illinois, 60654, United States

Location

Galderma Study Site

Omaha, Nebraska, 68144, United States

Location

MeSH Terms

Interventions

abobotulinumtoxinA

Results Point of Contact

Title
Clinical Project Manager
Organization
Q-Med AB

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
phase 4
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 19, 2018

First Posted

September 27, 2018

Study Start

October 2, 2018

Primary Completion

November 7, 2019

Study Completion

December 4, 2019

Last Updated

August 26, 2022

Results First Posted

March 18, 2020

Record last verified: 2020-03

Data Sharing

IPD Sharing
Will not share

Locations