Hypocalcemia in Infants and Children
Profile of Hypocalcemia in Infants and Children Admitted to Assiut University Children Hospital
1 other identifier
observational
30
0 countries
N/A
Brief Summary
Hypocalcemia is defined as reduction in the level of the ionized calcium in the blood to less than 0.95 mmole/ litre. In some cases it is associated with symptoms such as neuromuscular impairment in the form of convulsions ,carpopedal spasm,parathesia ,laryngiospasm ,stridor……etc .Calcium circulates in blood stream in three fractions :protein bound to calcium,primarly to albumen(40%) and in 50% of the cases calcium is present in the ionized state which is physiologically active (Dias ,c et a l, 2013) . Symptomatizing hypocalcemia may occur in cases of vitamin D deficiency rickets (nutritional deficiency in infants less than two years ) .It may also occur in vitamin D resistant rickets e.g renal rickets because of failure of the kidney to synthesize 1-OH cholecalciferol of the 1-25 di-OH cholecalciferol (the active form of vitamin D).
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for all trials
Started Mar 2019
Shorter than P25 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
September 24, 2018
CompletedFirst Posted
Study publicly available on registry
September 26, 2018
CompletedStudy Start
First participant enrolled
March 30, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 30, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
April 1, 2020
CompletedFebruary 26, 2019
September 1, 2018
Same day
September 24, 2018
February 23, 2019
Conditions
Outcome Measures
Primary Outcomes (1)
hypocalcemia in infants and children
Good management of all cases with symptomatizing hypocalcemia admitted at Assiut University Children Hospital based on knowing the exact final diagnosis by knowing the result of the various investigations as indicated
1YEAR
Secondary Outcomes (1)
pediatric hypocalcemia
1YEAR
Eligibility Criteria
: All data will be collected in a sheet form for all cases of acutely symptomatizing hypocalcemia admitted during period from 1st November 2018 to End of November 2019.
You may qualify if:
- All symptomatizing hypocalcemic cases presenting acutely to the Assiut University Children Hospital with convulsions, carpopedal spasm, stridor, renal symptoms or malabsorption symptoms aged \> 1 month to the age of 17 years.
You may not qualify if:
- All neonatal hypocalcemic cases.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- OTHER
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Profile of hypocalcemia in infants and children admitted to Assiut University Children Hospital.
Study Record Dates
First Submitted
September 24, 2018
First Posted
September 26, 2018
Study Start
March 30, 2019
Primary Completion
March 30, 2019
Study Completion
April 1, 2020
Last Updated
February 26, 2019
Record last verified: 2018-09