Correlation Between Idiopathic Parkinson's Disease and Diabetes Mellitus
Investigation of the Possible Correlation Between Idiopathic Parkinson's Disease and Diabetes Mellitus in Egyptian Elderly Patients
1 other identifier
observational
120
1 country
1
Brief Summary
Correlation between Idiopathic Parkinson's disease and diabetes mellitus in Egyptian Elderly Patients
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Jul 2018
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
July 1, 2018
CompletedFirst Submitted
Initial submission to the registry
September 22, 2018
CompletedFirst Posted
Study publicly available on registry
September 26, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
January 1, 2020
CompletedSeptember 27, 2018
September 1, 2018
11 months
September 22, 2018
September 25, 2018
Conditions
Outcome Measures
Primary Outcomes (3)
UPDRS (Unified Parkinson's Disease Rating) Scale)
Association between glucose level and motor complication of L-dopa among Idiopathic , , Parkinson's patients using Unified Parkinson's Disease Rating Scale (UDPRS)., high scores mean worsen condition
Baseline
Oral Glucose Tolerance Test
Between Idiopathic Parkinson's patients and the Control group
0, 0.5 hour , 1 hour, 1.5 hour , 2 hour
RBDSQ ("Rapid eye movement Sleep" Behavior Disorder Screening Questionnaire)
among Diabetic Patients, total score 13 , high scores mean worsen condition
Baseline
Study Arms (4)
Idiopathic Parkinson's
Oral glucose tolerance test The Unified Parkinson's Disease Rating Scale (UDPRS).
Diabetics receive sulphonylurea group
Record RBDSQ ("Rapid eye movement Sleep" Behavior Disorder Screening Questionnaire) total score
Diabetics on sulphonylurea and metformin
Record RBDSQ ("Rapid eye movement Sleep" Behavior Disorder Screening Questionnaire) total score
Healthy
Record RBDSQ ("Rapid eye movement Sleep" Behavior Disorder Screening Questionnaire) total score Oral glucose tolerance test
Eligibility Criteria
Egyptian Elderly
You may qualify if:
- Diabetic Patients
- Idiopathic Parkinsonism
You may not qualify if:
- Secondary Parkinsonism due to stroke, trauma and encephalitis.
- Drug induced Parkinsonism.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Ain Shams Universitylead
- Al-Azhar Universitycollaborator
Study Sites (1)
AinShams University
Cairo, Egypt
Related Publications (1)
AwadAllah Elgnainy A, Hamed MI, Osman Mohamed W, Sabri NA. Investigation of the Possible Correlation between Idiopathic Parkinson's Disease and Diabetes Mellitus in Egyptian Patients: A Pilot Study. Neurol Res Int. 2021 Nov 12;2021:2838669. doi: 10.1155/2021/2838669. eCollection 2021.
PMID: 34804608DERIVED
Biospecimen
Blood Samples
Study Officials
- PRINCIPAL INVESTIGATOR
Afnan Elgnainy
AinShams University
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Master student, teaching assistant of Clinical Pharmacy
Study Record Dates
First Submitted
September 22, 2018
First Posted
September 26, 2018
Study Start
July 1, 2018
Primary Completion
June 1, 2019
Study Completion
January 1, 2020
Last Updated
September 27, 2018
Record last verified: 2018-09