NCT03681236

Brief Summary

Investigating the effect of alveolar recruitment on the incidence of postoperative pulmonary complication in patients who undergo laparoscopic surgery

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
138

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Oct 2018

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 20, 2018

Completed
4 days until next milestone

First Posted

Study publicly available on registry

September 24, 2018

Completed
10 days until next milestone

Study Start

First participant enrolled

October 4, 2018

Completed
5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 4, 2023

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 6, 2023

Completed
Last Updated

May 12, 2022

Status Verified

May 1, 2022

Enrollment Period

5 years

First QC Date

September 20, 2018

Last Update Submit

May 10, 2022

Conditions

Keywords

Alveolar recruitment, laparoscopic surgery

Outcome Measures

Primary Outcomes (1)

  • Postoperative pulmonary complication

    Performing lung ultrasound to evaluate if pulmonary complication is occurred

    Immediately after entering PACU

Study Arms (2)

No alveolar recruitment maneuver

NO INTERVENTION

Applying ventilation with tidal volume 6-8mL/kg (ideal body weight) and PEEP 5cmH₂O

Alveolar recruitment maneuver

ACTIVE COMPARATOR

Applying ventilation with tidal volume 6-8mL/kg (ideal body weight) and PEEP 5cmH₂O. In addition to this, performing alveolar recruitment maneuver at 2 moments: before surgical incision, end of pneumoperitoneum

Procedure: Alveolar recruitment maneuver

Interventions

Applying plateau pressure 30cmH₂O for 30 seconds to achieve alveolar inflation

Alveolar recruitment maneuver

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adult patients, ASA I-II, scheduled to elective laparoscopic surgery

You may not qualify if:

  • Chronic lung disease
  • Cardiovascular disease
  • ASA class ≥ III
  • Receiving ventilation therapy or received within 6 months
  • Refusal of participation in study or failure in informed consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Seoul National University Bundang Hospital, department of Anesthesia and pain

Seongnam, Gyenggo-do, 13620, South Korea

RECRUITING

Related Publications (1)

  • Bae YK, Nam SW, Oh AY, Kim BY, Koo BW, Han J, Yim S. Effect of the alveolar recruitment maneuver during laparoscopic colorectal surgery on postoperative pulmonary complications: A randomized controlled trial. PLoS One. 2024 May 9;19(5):e0302884. doi: 10.1371/journal.pone.0302884. eCollection 2024.

Study Officials

  • Ah Young Oh, M.D., Ph. D

    Seoul National University Bundang Hospital

    STUDY DIRECTOR

Central Study Contacts

Sun Woo Nam, M.D

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant professor

Study Record Dates

First Submitted

September 20, 2018

First Posted

September 24, 2018

Study Start

October 4, 2018

Primary Completion

October 4, 2023

Study Completion

December 6, 2023

Last Updated

May 12, 2022

Record last verified: 2022-05

Data Sharing

IPD Sharing
Will not share

Locations