NCT03676855

Brief Summary

Comparison between bladder dissection at the beginning of cesarean section For morbidly adherent placenta and between delaying dissection until planning for cesarean hysterectomy

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Mar 2018

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 31, 2018

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

August 26, 2018

Completed
24 days until next milestone

First Posted

Study publicly available on registry

September 19, 2018

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2019

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 31, 2019

Completed
Last Updated

September 19, 2018

Status Verified

September 1, 2018

Enrollment Period

10 months

First QC Date

August 26, 2018

Last Update Submit

September 16, 2018

Conditions

Outcome Measures

Primary Outcomes (3)

  • Operative time

    of whole cs

    icluding all cs over the period of one year

  • Blood loss

    through counting soaked towels and weighting them before and after being soaked considering the difference in grams as the calculated blood loss and calculating blood in the suction reservoir and comparing pre and post operative Hb level also haemotacrit level and number of units of packed RBCs transfused

    icluding all cs over the period of one year

  • - Incidence of urological

    \- Incidence of urological injuries discovered intraoperative and procedure needed to repair or as a late complication as fistula formation.

    during cs and post operative delayed complication icluding all cs over the period of one year

Secondary Outcomes (3)

  • Neonatal APGAR score

    after delivery of the baby during the 1st 15 minutes

  • Time taken to create bladder flap

    from the start of bladder dissection icluding all cs over the period of one year

  • 3 months post operative filling cystometry

    3 months post operative

Study Arms (2)

bladder dissection before uterine incision

ACTIVE COMPARATOR
Procedure: bladder dissection

bladder dissection after uterine incision

EXPERIMENTAL
Procedure: bladder dissection

Interventions

Comparison between bladder dissection at the beginning of cesarean section For morbidly adherent placenta and between delaying dissection until planning for cesarean hysterectomy

bladder dissection after uterine incisionbladder dissection before uterine incision

Eligibility Criteria

Age18 Years - 50 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Women with BMI at or under 35 Kg/m2.
  • Women having previous two cesarean section or more.
  • Women with gestational age more than 32 weeks with viable fetus.
  • Women with any degree of placenta previa .
  • Patient with morbidly adherent placenta on cesarean scar only.

You may not qualify if:

  • Patient who are haemodynamically unstable before skin incision.
  • Patient with clinically evident intraamniotic infection.
  • Patient with previous history of bladder injury .

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ain Shams University Maternity Hospital

Cairo, 02, Egypt

RECRUITING

MeSH Terms

Conditions

Placenta Accreta

Condition Hierarchy (Ancestors)

Obstetric Labor ComplicationsPregnancy ComplicationsFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesPlacenta Diseases

Central Study Contacts

hassan helmy, master

CONTACT

mohamed elsenity, MD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Lecturer of obs and gyn atainshams university

Study Record Dates

First Submitted

August 26, 2018

First Posted

September 19, 2018

Study Start

March 31, 2018

Primary Completion

February 1, 2019

Study Completion

March 31, 2019

Last Updated

September 19, 2018

Record last verified: 2018-09

Data Sharing

IPD Sharing
Will share

Locations