Pregnancy Loss Between 15 and 22 Weeks SA Within the Network of Perinatal Pérriodof Western Brittany : Case Control Study PILOT STUDY CA

NCT03668743 | Completed

• 1 other identifier: PEGREP (29BRC17.0056)
• Study Type: observational
• Target: 202
• Locations: 1 country
• Sites: 2

Brief Summary

The etiologies and some risk factors for pregnancy loss in the 2nd trimester are described in the literature. However, there are some risk factors that are not studied. The PEGREP study is a retrospective observational case-control study whose main objective is to identify risk factors for pregnancy loss between 15 and 22 weeks. The patients included cases are women who had a pregnancy loss between 15 and 22 SA between 2010 and 2015 and who were listed during the mortality reviews of the perinatal network of Western Brittany. The patient witnesses gave birth at the end of a healthy child in one of the maternity of Western Brittany. Matching 1 case for 1 controls was done on the woman's age, parity and number of fetuses.

Conditions

Miscarriage in Second Trimester

Keywords

risk factor

Outcome Measures

Primary Outcomes (2)

• maternal history

  chronic diseases, history of gynecology and obstetrics

  at the time of diagnosis of fetal loss (Day1)

• criteria of the pregnancy concerned by the fetal loss

  pregnancy after infertility treatment, antenatal invasiveness, 1st trimester, premature bleeding, gestational diabètes, rupture of membranes

  at the time of diagnosis of fetal loss ( Day 1)

Eligibility Criteria

• Age: 18 Years - 50 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

Patients who had a loss of pregnancy between 15 and 22 SA between 2010 and 2015, listed thanks to the data sheets of the perinatal network of Western Brittany

You may qualify if:

• CAS:
• patients who had a pregnancy loss between 15 and 22 SA between 2010 and 2015
• having given birth in one of the maternities of Western Brittany
• listed during the mortality reviews of the perinatal network of Western Brittany.
• WITNESSES:
• patients who have given birth (\> 37SA) of healthy children
• having given birth in one of the maternity of Western Brittany. Pairing: Age, parity, number of fetuses (single or multiple pregnancy). Pairing 1 case for 1 witnesses.
• Listed at Brest CHRU

You may not qualify if:

• Pregnancy loss after 22 weeks,
• medical or therapeutic interruptions of pregnancy,
• fetuses whose anatomopathology describes biometrics below 15SA,
• fetuses with chromosomal malformations or abnormalities diagnosed before pregnancy loss.

Sponsors & Collaborators

• University Hospital, Brest: lead

Study Sites (2)

SALAUN Anne -Laure

Brest, 29200, France

Location

CHRU de Brest

Brest, 29609, France

Location

Study Officials

• Anne-Laure SALAUN

  University Hospital, Brest

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 11, 2018
• First Posted: September 13, 2018
• Study Start: June 1, 2017
• Primary Completion: November 1, 2017
• Study Completion: November 1, 2017
• Last Updated: September 13, 2018

Record last verified: 2017-05

Locations

FR (2)