NCT03667950

Brief Summary

In this study, gastrointestinal anastomoses are examined with a hyperspectral camera.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
200

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Aug 2018

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2018

Completed
29 days until next milestone

First Submitted

Initial submission to the registry

August 30, 2018

Completed
13 days until next milestone

First Posted

Study publicly available on registry

September 12, 2018

Completed
2.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2020

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2021

Completed
Last Updated

October 31, 2019

Status Verified

October 1, 2019

Enrollment Period

2.3 years

First QC Date

August 30, 2018

Last Update Submit

October 29, 2019

Conditions

Keywords

anastomotic perfusion, tissue oxygen saturation

Outcome Measures

Primary Outcomes (4)

  • Anastomotic Perfusion: (Oxygenation (StO2)

    Oxygenation (StO2) in %: Relative O2 saturation of the blood immicrocircular system in superficial tissue layers (penetration depth: approx. 1 mm)

    direct during the Operation (ca. 15-20 Minutes)

  • Anastomotic Perfusion: Tissue-Hemoglobin index

    Tissue Hemoglobin index in %: Existing hemoglobin distribution in the microcircular system of the tissue area under consideration (index value)

    direct during the Operation (ca. 15-20 Minutes)

  • Anastomotic Perfusion: Near Infrared Perfusion Index

    Near Infrared Perfusion Index in %: Relative O2 saturation of the blood immicrocircular system in deeper tissue layers (penetration depth: 4-6mm; index value)

    direct during the Operation (ca. 15-20 Minutes)

  • Anastomotic Perfusion: Tissue-Water-Index

    Tissue-Water-Index in %: Existing water distribution in the tissue area under consideration (index value)

    direct during the Operation (ca. 15-20 Minutes)

Study Arms (1)

hyperspectral imaging

EXPERIMENTAL

diagnostic hyperspectral Imaging of the gastrointestinal anastomosis and calculating the anastomotic Perfusion measures

Procedure: Hyperspectral Imaging

Interventions

Photos were taken with the hyperspectral camera of the gastrointestinal anastomosis.

hyperspectral imaging

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • all gastrointestinal anastomoses

You may not qualify if:

  • inability to consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Universitätsklinikum Leipzig - AöR

Leipzig, Saxony, 04103, Germany

RECRUITING

Related Publications (1)

  • Jansen-Winkeln B, Maktabi M, Takoh JP, Rabe SM, Barberio M, Kohler H, Neumuth T, Melzer A, Chalopin C, Gockel I. [Hyperspectral imaging of gastrointestinal anastomoses]. Chirurg. 2018 Sep;89(9):717-725. doi: 10.1007/s00104-018-0633-2. German.

    PMID: 29637244BACKGROUND

MeSH Terms

Interventions

Hyperspectral Imaging

Intervention Hierarchy (Ancestors)

Spectrum AnalysisChemistry Techniques, AnalyticalInvestigative Techniques

Study Officials

  • Boris Jansen-Winkeln, Dr.

    University of Leipzig

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Ines Gockel, Prof. Dr.

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr.

Study Record Dates

First Submitted

August 30, 2018

First Posted

September 12, 2018

Study Start

August 1, 2018

Primary Completion

December 1, 2020

Study Completion

January 1, 2021

Last Updated

October 31, 2019

Record last verified: 2019-10

Data Sharing

IPD Sharing
Will not share

no sharing

Locations